Cardiovascular

A Health Coach-Based Multilevel Personalized Strategy Lowers Low-Density Lipoprotein Cholesterol and Enhances Lipid Control in Veterans With Atherosclerotic Cardiovascular Disease.

TL;DR

Health coach-delivered interventions to improve medication adherence and encourage lifestyle modifications led to significant LDL-C reduction, with 42.6% achieving control, surpassing the 30% program benchmark, and lowered LDL-C level.

Key Findings

Median LDL-C decreased significantly from baseline to follow-up among veterans with atherosclerotic cardiovascular disease engaged by health coaches.

  • Median baseline LDL-C was 92.0 mg/dL (interquartile range 81.0–118.0 mg/dL)
  • Median follow-up LDL-C was 75.0 mg/dL (interquartile range 54.5–98.0 mg/dL)
  • Mean LDL-C change from baseline was -22.7 mg/dL
  • Statistical significance confirmed by Wilcoxon signed rank test, P<0.001
  • Sample size was 152 engaged veterans

The proportion of veterans achieving controlled LDL-C (<70 mg/dL) was 42.6%, surpassing the program benchmark of 30%.

  • 42.6% of the 152 engaged veterans achieved LDL-C <70 mg/dL at follow-up
  • The program benchmark target was >30% of veterans with atherosclerotic cardiovascular disease and uncontrolled LDL-C achieving LDL-C <70 mg/dL
  • Statistical significance confirmed by binomial test, P=0.001

At baseline, the majority of engaged veterans had moderately to severely elevated LDL-C levels.

  • 57.9% of veterans had baseline LDL-C between 70 and 100 mg/dL
  • 41.4% had baseline LDL-C ≥100 mg/dL
  • 0.7% had no LDL-C data in the past year
  • All enrolled veterans had uncontrolled LDL-C (≥70 mg/dL) and a diagnosis of atherosclerotic cardiovascular disease

LDL-C was significantly lowered across almost all specialty care groups, with no statistically significant difference in LDL-C control rates between specialties.

  • All specialties except geriatrics achieved statistically significant LDL-C lowering
  • All specialties except geriatrics exceeded the 30% LDL-C control goal
  • LDL-C control rates did not statistically differ by specialty (Fisher exact test, P=0.091)

Health coaches used a multilevel, personalized strategy incorporating root-cause analysis, medication possession ratio assessment, and motivational interviewing to address barriers to lipid control.

  • Medication possession ratio (MPR) was used to assess medication adherence
  • Veterans with MPR <0.8 received interventions targeting adherence barriers
  • Veterans with MPR ≥0.8 were facilitated toward medication intensification
  • Motivational interviewing principles were applied to improve medication adherence and lifestyle habits
  • The project was part of the Veterans Affairs Lipid Optimization Reimagined Quality Improvement Project, involving 50 VA sites working with an American Heart Association quality improvement consultant

What This Means

This research describes a quality improvement project at a Veterans Affairs healthcare system in New York that used health coaches to help veterans with heart disease lower their 'bad' cholesterol (LDL-C). The health coaches used structured conversations and motivational techniques to identify why each veteran was struggling to control their cholesterol — whether it was difficulty taking their medications consistently or a need for stronger medications — and then tailored their support accordingly. The study compared cholesterol levels before and after the health coach program among 152 veterans who participated. This research suggests that the health coach approach produced meaningful results: average LDL-C dropped by about 22.7 mg/dL, and 42.6% of participants achieved a target LDL-C below 70 mg/dL, which exceeded the program's goal of getting at least 30% of participants to that level. The reductions were seen across nearly all types of medical specialty care involved, and the program's success did not differ significantly depending on which specialty was involved. This research suggests that embedding health coaches into cardiovascular care — with a structured, personalized framework — can be an effective strategy for helping patients with heart disease achieve better cholesterol control. This is significant because uncontrolled LDL-C in people with existing heart disease substantially raises the risk of heart attacks and strokes, and many patients face real-world barriers to taking medications as prescribed or making lifestyle changes. The use of a practical, scalable model within an existing healthcare system like the VA may offer a template for other health systems seeking to improve cholesterol management at a population level.

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Citation

Chen T, Ingerman D, Haley L, Salovaara P, Nicholson A, Illenberger N, et al.. (2026). A Health Coach-Based Multilevel Personalized Strategy Lowers Low-Density Lipoprotein Cholesterol and Enhances Lipid Control in Veterans With Atherosclerotic Cardiovascular Disease.. Journal of the American Heart Association. https://doi.org/10.1161/JAHA.125.047697