The mental health of young and middle-aged orthodontic patients follows a dynamic trajectory associated with a combination of sociodemographic and clinical factors, with female gender, student status, unmarried status, and severe malocclusion as risk factors, while strong social support is protective.
Key Findings
Results
Mental health scores among orthodontic patients showed a significant temporal trend across the 15-month treatment period.
The GEE model indicated a significant temporal trend in mental health scores (Wald χ² = 304.51, p < 0.001)
Data were collected at eight time points from treatment initiation to 15 months
154 patients were recruited from Nantong Stomatological Hospital between March 2023 and October 2024
Psychological distress was measured using the Kessler 10 (K10) scale
Results
Female gender was associated with significantly higher psychological distress scores in orthodontic patients.
Female gender was associated with higher K10 scores (β = 6.12, p < 0.001)
This was among the largest effect sizes observed in the GEE model
The study used generalized estimating equations (GEE) to analyze mental health trajectories longitudinally
Results
Student status and unmarried status were each independently associated with poorer mental health outcomes.
Student status was associated with higher psychological distress (β = 2.18, p = 0.020)
Unmarried status was associated with higher psychological distress (β = 3.05, p = 0.010)
These factors were identified as risk factors alongside female gender and severe malocclusion
Results
Higher monthly household income and higher educational attainment were associated with lower psychological distress scores.
Monthly household income greater than 10,000 RMB was associated with lower K10 scores (β = -3.51, p < 0.001)
Having a Bachelor's degree or above was associated with lower K10 scores (β = -1.89, p < 0.001)
Both factors were statistically significant protective sociodemographic variables in the GEE model
Results
Severe malocclusion (Class III) was associated with significantly higher psychological distress compared to less severe presentations.
Class III malocclusion was associated with higher K10 scores (β = 1.23, p = 0.018)
This was the only clinical (non-sociodemographic) factor found to be a significant risk factor
Malocclusion severity was identified as a factor warranting psychological monitoring during orthodontic care
Results
Social support was identified as a significant protective factor against psychological distress in orthodontic patients.
Higher social support was associated with lower K10 scores (β = -0.35, p < 0.001)
Social support was measured using the Social Support Rating Scale (SSRS)
Social support was the only modifiable protective factor identified in the GEE model
The authors concluded that strong social support is protective throughout orthodontic care
Methods
A propensity score matching approach was used to establish a balanced control cohort for comparison.
A 1:1 propensity score matching (PSM) control cohort was established to balance demographic characteristics
The study enrolled 154 orthodontic patients and matched them with a control cohort
Eight time points were used for data collection over a 15-month period
General information, social support, and psychological distress data were all collected at each time point
What This Means
This research suggests that the mental health of people undergoing orthodontic (braces) treatment is not static — it changes over time in predictable patterns across a 15-month treatment course. Researchers followed 154 young and middle-aged patients in China, measuring their psychological distress and social support at eight different points during treatment. They found that certain groups of patients consistently experienced more psychological distress: women, students, unmarried individuals, and those with more severe teeth misalignment (Class III malocclusion). In contrast, patients with higher incomes, more education, and stronger social support systems tended to have better mental health throughout treatment.
The finding that social support acts as a protective factor is particularly notable, as it is a potentially changeable factor — meaning that encouraging family and community support during orthodontic treatment could help buffer against psychological distress. The severity of the dental problem itself (Class III malocclusion) also independently worsened mental health, suggesting that the physical challenge of more complex cases adds psychological burden beyond just the treatment process.
This research suggests that orthodontic care providers should not only focus on the physical aspects of treatment but also consider the mental well-being of their patients, particularly those who belong to higher-risk groups. Routine psychological monitoring and personalized support strategies — especially for female patients, students, those without partners, and those with severe malocclusion — could improve both the treatment experience and overall well-being during what can be a lengthy and physically noticeable medical process.
Miao X, Zhang Y, Xiong B, Liang M. (2026). A longitudinal study on the mental health status of young and middle-aged orthodontic patients.. Acta odontologica Scandinavica. https://doi.org/10.2340/aos.v85.46107