A precision intervention model combining wearable devices (continuous glucose monitoring) and standardized health education courses effectively improved glycemic metabolic parameters and health behaviors in community-dwelling adults with impaired glucose tolerance.
Key Findings
Results
Of 1,047 high-risk individuals screened, 278 were diagnosed with IGT and 191 (97 intervention, 94 control) completed the study.
Prospective, non-randomized controlled community-based intervention conducted May to December 2025 in five pilot areas in Zhejiang Province.
Participants were aged 35-60 years and diagnosed with IGT by oral glucose tolerance testing.
Within each community, participants were frequency-matched by age and sex and allocated to the intervention or control group.
Data were collected at baseline, day 28, and day 90.
Methods
The intervention consisted of a 28-day program plus a 60-day consolidation phase, compared with routine community health management in controls.
The 28-day intervention comprised continuous glucose monitoring, individualized exercise and dietary guidance, and structured health education courses.
A 60-day consolidation management phase followed.
The control group received routine community health management.
Analyses used t-tests, chi-square tests, generalized linear models, and repeated-measures ANOVA.
Results
After the intervention, the proportion of intervention-group participants exercising regularly and following a healthy diet increased, with significant between-group differences.
Regular exercise rate rose from 38.10% to 41.20% in the intervention group.
Healthy diet adherence rose from 40.20% to 47.40%.
Between-group differences were statistically significant (P<0.05).
Results
By day 90, 2-hour postprandial plasma glucose and fasting plasma glucose decreased in the intervention group, with significant group-by-time interactions.
2-hour postprandial glucose fell from (9.26±0.94) to (6.57±2.00) mmol/L (F=7.05, P=0.009).
FPG fell from (5.51±0.57) to (5.29±0.53) mmol/L (F=4.83, P=0.009).
Results
BMI decreased in the intervention group by day 90 with a significant group-by-time interaction.
BMI fell from (25.45±3.94) to (24.63±3.34) kg/m².
Group-by-time interaction: F=6.34, P=0.013.
Results
Fasting insulin and 2-hour postprandial insulin decreased significantly in the intervention group.
Fasting insulin: (10.53±5.42) vs. (8.96±4.67) mIU/L (group-by-time P=0.022).
2-hour postprandial insulin: (108.49±74.45) vs. (63.08±55.79) mIU/L (group-by-time P=0.016).
Conclusions
The study established a dynamic management pathway of 'screening, assessment, individualized intervention, follow-up, and feedback adjustment' as a preliminary implementation pathway for community-based prediabetes prevention.
The authors conclude the wearable-plus-standardized-course model effectively improved glycemic metabolic parameters and health behaviors in adults with IGT.
The pathway is described as preliminary.
What This Means
This study tested a community program for adults aged 35-60 with impaired glucose tolerance, a prediabetes condition. The program used a wearable continuous glucose monitor, personalized exercise and diet advice, and structured health education classes over 28 days, followed by 60 days of continued support. A comparison group received usual community health care. In total, 191 people completed the study (97 in the program, 94 in the comparison group).
People in the program were more likely to exercise regularly and eat healthily afterward. By day 90, their blood sugar after a glucose challenge dropped from about 9.3 to 6.6 mmol/L, and fasting blood sugar, body mass index, and insulin levels also fell, with significant differences in how these changed over time compared with the control group.
This research suggests that combining wearable glucose monitoring with structured education may help improve blood sugar and lifestyle habits in people with prediabetes in community settings. However, participants were not randomly assigned, the follow-up was only 90 days, and many screened people did not complete the study, so the results are preliminary and the long-term effect on diabetes risk is not known.
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Xu Y, Lyu Q, Hu X, Yao D, Zhang X, He Q, et al.. (2026). [A study on health behavior interventions in individuals with impaired glucose tolerance].. Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi. https://doi.org/10.3760/cma.j.cn112338-20260203-00091