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Adolescent wellbeing is associated with positive outcomes in early adulthood in a sibling comparison study.

TL;DR

Higher adolescent wellbeing (age 14-16) is associated with more favourable psychological and health-related outcomes in early adulthood, with associations persisting after controlling for shared familial factors in within-family sibling comparison analyses.

Key Findings

Higher adolescent wellbeing was positively associated with early adulthood wellbeing in between-family analyses.

  • Study used data from 14,518 twins and siblings of the Netherlands Twin Register
  • Adolescent wellbeing was measured at ages 14-16; early adulthood outcomes were assessed at ages 20-25 and 25-35
  • Between-family standardized beta coefficients for adult wellbeing ranged from β = 0.32 to 0.38 (pFDR < 0.05)
  • Within-family analysis (controlling for shared familial factors) also showed a significant association at ages 20-25 (β = 0.12, pFDR < 0.05), though attenuated compared to between-family estimates

Higher adolescent wellbeing was positively associated with flourishing in early adulthood in both between-family and within-family analyses.

  • Between-family beta coefficients for flourishing ranged from β = 0.27 to 0.34 (pFDR < 0.05)
  • Within-family analysis at ages 20-25 yielded β = 0.17 (pFDR < 0.05)
  • Attenuation of the association was observed in within-family relative to between-family analyses, suggesting shared familial factors partially explain the relationship
  • Flourishing was assessed as an outcome in early adulthood (ages 20-25 and 25-35)

Higher adolescent wellbeing was associated with better sleep quality in early adulthood, and this association persisted after adjusting for adolescent sleep levels and shared familial factors.

  • Between-family beta coefficients for sleep quality ranged from β = 0.59 to 0.87 (pFDR < 0.05)
  • Within-family beta coefficients for sleep quality ranged from β = 0.46 to 0.71 (pFDR < 0.05)
  • The association remained significant after adjusting for adolescent levels of sleep quality (β = 0.59; 0.66, pFDR < 0.05)
  • Sleep quality showed among the largest effect sizes of all outcomes examined

Higher adolescent wellbeing was inversely associated with neuroticism in early adulthood, with the association persisting after adjusting for adolescent neuroticism and within-family controls.

  • Between-family beta coefficients for neuroticism ranged from β = -0.34 to -0.11 (pFDR < 0.05)
  • After adjusting for adolescent levels of neuroticism, the association remained significant (β = -0.11 to -0.37, pFDR < 0.05)
  • Within-family analysis at ages 20-25 yielded β = -0.12 (pFDR < 0.05)
  • Neuroticism was one of the personality trait outcomes assessed alongside conscientiousness

Higher adolescent wellbeing was positively associated with conscientiousness in early adulthood in between-family analyses.

  • Between-family beta coefficients for conscientiousness ranged from β = 0.18 to 0.22 (pFDR < 0.05)
  • Conscientiousness was assessed as a personality trait outcome in early adulthood
  • The paper does not report a significant within-family result for conscientiousness in the abstract, suggesting attenuation to non-significance after controlling for shared familial factors

Higher adolescent wellbeing was positively associated with self-rated health in early adulthood, and this association persisted after adjusting for adolescent health levels and within-family controls.

  • Between-family beta coefficients for self-rated health ranged from β = 0.09 to 0.18 (pFDR < 0.05)
  • After adjusting for adolescent levels of self-rated health, the association remained significant (β = 0.09, pFDR < 0.05)
  • Within-family analysis at ages 20-25 also showed a significant association (β = 0.07, pFDR < 0.05)
  • Self-rated health showed smaller effect sizes relative to wellbeing, flourishing, and sleep quality

Within-family sibling comparison analyses generally showed attenuated but often still significant associations between adolescent wellbeing and early adulthood outcomes compared to between-family analyses.

  • Within-family designs control for shared familial factors including genetics, shared environment, and family-level confounders
  • Significant within-family associations were observed for wellbeing (β = 0.12), flourishing (β = 0.17), self-rated health (β = 0.07), sleep quality (β = 0.46–0.71), and neuroticism (β = -0.12) at ages 20-25 (pFDR < 0.05)
  • The attenuation from between-family to within-family estimates suggests shared familial factors partly but not entirely account for the observed associations
  • The study used both between-family and within-family designs as a methodological strategy to assess the robustness of associations

The study used a large sample of twins and siblings from the Netherlands Twin Register with both between-family and within-family analytical designs.

  • Total sample comprised 14,518 twins and siblings
  • Adolescent wellbeing was assessed at ages 14-16
  • Adult outcomes were assessed at two time points: ages 20-25 and ages 25-35
  • Outcomes included adult wellbeing, flourishing, personality traits (conscientiousness and neuroticism), self-rated health, and sleep quality
  • False discovery rate (FDR) correction was applied to account for multiple comparisons (pFDR < 0.05 threshold)

What This Means

This research suggests that how well teenagers feel during adolescence (ages 14-16) is meaningfully linked to a range of positive outcomes when they become young adults. Using data from over 14,000 Dutch twins and siblings, researchers found that teens who reported higher wellbeing went on to have better mental wellbeing, a greater sense of flourishing, healthier self-rated health, better sleep quality, higher conscientiousness, and lower neuroticism (emotional instability) in their 20s and early 30s compared to teens with lower wellbeing. A key strength of this study is that it used a sibling comparison approach, which helps rule out explanations based on shared family background — things like growing up in the same household, having the same parents, or sharing genetic factors. Even after accounting for these shared influences, several associations remained statistically significant, particularly for wellbeing, flourishing, self-rated health, sleep quality, and neuroticism. This suggests the links between adolescent wellbeing and adult outcomes are not simply due to coming from a similar family environment, though shared family factors do partially explain the relationships. This research matters because it provides prospective evidence — following people over time rather than asking them to recall the past — that adolescent wellbeing is not just important in the moment but may have lasting implications into early adulthood. The findings highlight adolescence as a potentially important window where supporting young people's psychological wellbeing could have broad benefits across mental health, personality development, physical health, and sleep in the years that follow.

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Citation

Geijsen A, Bartels M. (2026). Adolescent wellbeing is associated with positive outcomes in early adulthood in a sibling comparison study.. Nature communications. https://doi.org/10.1038/s41467-026-72459-9