Cardiovascular

American Heart Association Life's Essential 8 and Heart Failure in Black Individuals: An Analysis of the National Health and Nutrition Examination Survey.

TL;DR

Black individuals in NHANES were diagnosed with heart failure at significantly younger ages than White individuals, and BMI, hypertension, hyperlipidemia, and diabetes were each independently associated with higher odds of HF while physical activity was associated with lower odds, underscoring the importance of early, targeted prevention strategies.

Key Findings

Black individuals were diagnosed with heart failure at a younger age than White individuals.

  • Mean age at HF diagnosis was 54 years in Black individuals vs 65 years in White individuals (P<0.001).
  • Analysis used NHANES data from 1999 to 2020, with 107,622 individuals categorized by self-reported race.
  • HF diagnosis was based on self-report.

Higher body mass index was associated with increased odds of HF among Black individuals.

  • OR 1.041 (95% CI, 1.027-1.055), P=0.02.
  • Estimated using multivariable logistic regression models in Black individuals.

Hypertension was strongly associated with increased odds of HF among Black individuals.

  • OR 3.175 (95% CI, 2.14-4.69), P<0.0001.
  • Hypertension was based on self-reported diagnosis.

Hyperlipidemia was associated with increased odds of HF among Black individuals.

  • OR 1.36 (95% CI, 1.04-1.76), P=0.02.
  • Hyperlipidemia was based on self-reported diagnosis.

Diabetes was associated with increased odds of HF among Black individuals.

  • OR 2.07 (95% CI, 1.60-2.67), P≤0.0001.
  • Diabetes was based on self-reported diagnosis.

Physical activity was associated with lower odds of HF among Black individuals.

  • OR 0.564 (95% CI, 0.38-0.836), P=0.004.
  • Physical activity was self-reported and used as one of the Life's Essential 8 components.

The study evaluated a subset of Life's Essential 8 components using self-reported NHANES variables in a cross-sectional design.

  • Life's Essential 8 was represented by self-reported sleep duration, physical activity, smoking status, and dietary habits.
  • Self-reported diagnoses of diabetes, hyperlipidemia, hypertension, and HF were also included.
  • Cross-sectional design with multivariable logistic regression estimating ORs and 95% CIs.

What This Means

This study used a large U.S. national health survey (NHANES, 1999-2020, over 107,000 people) to look at heart failure among Black individuals and how it relates to the American Heart Association's "Life's Essential 8" heart-health behaviors and factors. Black individuals reported being diagnosed with heart failure about 11 years earlier than White individuals (average age 54 vs 65). Among Black participants, higher body mass index, high blood pressure, high cholesterol, and diabetes were each linked to higher odds of heart failure. High blood pressure showed the strongest link, with roughly three times the odds, and diabetes about twice the odds. Physical activity was linked to lower odds of heart failure, with about 44% lower odds than those who were less active. This research suggests that heart failure affects Black individuals earlier in life and that common, modifiable factors such as blood pressure, weight, blood sugar, cholesterol, and physical activity are tied to it. Because the study is cross-sectional and relies on self-reported information, it shows associations rather than proving cause and effect, but the authors emphasize the value of early, targeted prevention.

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Citation

Rasberry K, Oputa O, Boyd K, Agunbiade T, Awoyemi T, Gao J, et al.. (2026). American Heart Association Life's Essential 8 and Heart Failure in Black Individuals: An Analysis of the National Health and Nutrition Examination Survey.. Journal of the American Heart Association. https://doi.org/10.1161/JAHA.126.049656