American Heart Association's Life's Simple 7 for cardiovascular health assessment among Iranian adults: a national cross-sectional study from STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021.
Azadnajafabad S, Rezaei S, et al. • BMJ open • 2026
Despite favourable scores in some cardiovascular health metrics, critical gaps in diet and physical activity highlight the need for intensive public health efforts to enhance CVH in Iran, with ideal CVH status significantly associated with lower risks of major diseases such as ischaemic heart disease, diabetes and chronic kidney disease.
Key Findings
Results
The majority of Iranian adults achieved ideal levels for smoking, total cholesterol, and fasting plasma glucose.
Ideal smoking status prevalence: 80.1% (95% CI 79.3 to 81.0)
Ideal total cholesterol prevalence: 69.4% (95% CI 68.5 to 70.4)
Ideal fasting plasma glucose (FPG) prevalence: 61.0% (95% CI 60.0 to 62.1)
Study sample: 25,202 adult individuals aged 25 years and older from the Iran STEPS survey 2020–2021
Sex distribution of participants was 55.5% females
Results
Ideal BMI and blood pressure were each achieved by approximately one-third of the Iranian adult population.
Ideal BMI prevalence: 33.0% (95% CI 32.1 to 34.0)
Ideal blood pressure prevalence: 30.5% (95% CI 29.6 to 31.4)
Both metrics were categorised using the LS7 framework into poor, intermediate, and ideal levels
Results
Physical activity and healthy diet were the worst-performing cardiovascular health metrics among Iranian adults.
Only 13.3% (95% CI 12.6 to 14.0) of participants achieved ideal levels of physical activity
A mere 0.4% (95% CI 0.3 to 0.6) adhered to an ideal healthy diet
These two metrics represent the most critical gaps in cardiovascular health in the Iranian population
Diet was assessed using modified healthy diet score components within the LS7 framework
Results
Modest disparities in cardiovascular health metrics were observed across Iranian provinces and between sexes.
Sex distribution of the sample was 55.5% females
Province-level and sex-specific variations were identified across the seven LS7 metrics
Disparities were characterized as 'modest' by the authors
The findings emphasize the need for region- and sex-specific public health policies
Results
Ideal cardiovascular health status was significantly associated with lower risks of major chronic diseases.
Ideal CVH status was associated with lower risk of ischaemic heart disease
Ideal CVH status was associated with lower risk of diabetes
Ideal CVH status was associated with lower risk of chronic kidney disease
The association was described as 'significant' in the context of the LS7 framework applied to the Iranian population
Methods
The study used the American Heart Association's Life's Simple 7 framework to assess cardiovascular health in a nationally representative Iranian sample.
Seven factors were assessed: current smoking, BMI, physical activity level, modified healthy diet score components, total cholesterol, blood pressure, and fasting plasma glucose
Each factor was categorised into three levels: poor, intermediate, and ideal
Data were drawn from the Iran STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021 (conducted 2020–2021)
Sample size was 25,202 adult individuals aged 25 years and older
Study design was cross-sectional and nationally representative
Azadnajafabad S, Rezaei S, Almasi G, Ahmadi N, Golestani A, Rashidi M, et al.. (2026). American Heart Association's Life's Simple 7 for cardiovascular health assessment among Iranian adults: a national cross-sectional study from STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021.. BMJ open. https://doi.org/10.1136/bmjopen-2025-101858