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American Heart Association's Life's Simple 7 for cardiovascular health assessment among Iranian adults: a national cross-sectional study from STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021.

TL;DR

Despite favourable scores in some cardiovascular health metrics, critical gaps in diet and physical activity highlight the need for intensive public health efforts to enhance CVH in Iran, with ideal CVH status significantly associated with lower risks of major diseases such as ischaemic heart disease, diabetes and chronic kidney disease.

Key Findings

The majority of Iranian adults achieved ideal levels for smoking, total cholesterol, and fasting plasma glucose.

  • Ideal smoking status prevalence: 80.1% (95% CI 79.3 to 81.0)
  • Ideal total cholesterol prevalence: 69.4% (95% CI 68.5 to 70.4)
  • Ideal fasting plasma glucose (FPG) prevalence: 61.0% (95% CI 60.0 to 62.1)
  • Study sample: 25,202 adult individuals aged 25 years and older from the Iran STEPS survey 2020–2021
  • Sex distribution of participants was 55.5% females

Ideal BMI and blood pressure were each achieved by approximately one-third of the Iranian adult population.

  • Ideal BMI prevalence: 33.0% (95% CI 32.1 to 34.0)
  • Ideal blood pressure prevalence: 30.5% (95% CI 29.6 to 31.4)
  • Both metrics were categorised using the LS7 framework into poor, intermediate, and ideal levels

Physical activity and healthy diet were the worst-performing cardiovascular health metrics among Iranian adults.

  • Only 13.3% (95% CI 12.6 to 14.0) of participants achieved ideal levels of physical activity
  • A mere 0.4% (95% CI 0.3 to 0.6) adhered to an ideal healthy diet
  • These two metrics represent the most critical gaps in cardiovascular health in the Iranian population
  • Diet was assessed using modified healthy diet score components within the LS7 framework

Modest disparities in cardiovascular health metrics were observed across Iranian provinces and between sexes.

  • Sex distribution of the sample was 55.5% females
  • Province-level and sex-specific variations were identified across the seven LS7 metrics
  • Disparities were characterized as 'modest' by the authors
  • The findings emphasize the need for region- and sex-specific public health policies

Ideal cardiovascular health status was significantly associated with lower risks of major chronic diseases.

  • Ideal CVH status was associated with lower risk of ischaemic heart disease
  • Ideal CVH status was associated with lower risk of diabetes
  • Ideal CVH status was associated with lower risk of chronic kidney disease
  • The association was described as 'significant' in the context of the LS7 framework applied to the Iranian population

The study used the American Heart Association's Life's Simple 7 framework to assess cardiovascular health in a nationally representative Iranian sample.

  • Seven factors were assessed: current smoking, BMI, physical activity level, modified healthy diet score components, total cholesterol, blood pressure, and fasting plasma glucose
  • Each factor was categorised into three levels: poor, intermediate, and ideal
  • Data were drawn from the Iran STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021 (conducted 2020–2021)
  • Sample size was 25,202 adult individuals aged 25 years and older
  • Study design was cross-sectional and nationally representative

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Citation

Azadnajafabad S, Rezaei S, Almasi G, Ahmadi N, Golestani A, Rashidi M, et al.. (2026). American Heart Association's Life's Simple 7 for cardiovascular health assessment among Iranian adults: a national cross-sectional study from STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021.. BMJ open. https://doi.org/10.1136/bmjopen-2025-101858