PA engagement in cardio-oncology is shaped by dynamic interactions among capability, opportunity, and motivation across survivor and medical team member contexts, with sustained engagement remaining limited due to fluctuating symptoms, environmental constraints, and clinical uncertainties.
Key Findings
Results
Only 42% of cancer survivors in cardio-oncology care met recommended physical activity guidelines.
5 out of 12 survivors met recommended PA guidelines
Survivors had a mean age of 65.3 (SD 12.6) years and were evenly distributed by sex
PA engagement was assessed via survey as part of a mixed-methods design alongside qualitative interviews
Results
The mean cardiovascular health score among cancer survivors was 71.3 (SD 11.9) based on a modified Life's Essential 8 framework.
The modified LE8-derived score was a standardized 6-domain composite including diet, PA, nicotine exposure, sleep, BMI, and blood pressure
The composite was calculated identically for all 12 participants
Full LE8 domains (cholesterol and blood glucose) were excluded from the composite, representing a modification of the standard LE8 tool
Results
Physical limitation was the most commonly reported capability barrier to PA engagement among cancer survivors.
All 12 of 12 survivors reported physical limitation as a capability barrier
Barriers were identified through semistructured interviews and mapped to the Capability, Opportunity, Motivation-Behavior (COM-B) framework
Rapid qualitative analysis was used to identify and organize themes across COM-B domains
Results
Current engagement in PA was the most prevalent capability facilitator, reported by all cancer survivors.
12 out of 12 survivors identified current PA engagement as a capability facilitator
This finding suggests that existing activity behavior itself reinforces continued engagement
Facilitators were identified using the same COM-B framework and rapid qualitative analysis methodology
Results
Social environment was the most frequently cited opportunity facilitator for PA among both cancer survivors and medical team members.
12 out of 12 survivors cited social environment as an opportunity facilitator
9 out of 12 medical team members also cited social environment as an opportunity facilitator
Lack of access to PA resources was the most common opportunity barrier among medical team members (9/12)
Results
Perceived health outcomes was the most prevalent motivational facilitator for PA across both cancer survivors and medical team members.
12 out of 12 survivors identified perceived health outcomes as a motivational facilitator
7 out of 12 medical team members identified perceived health outcomes as a motivational facilitator
Competing motivational concerns included safety and emotional responses to PA
Results
Medical team members' ability to promote PA was influenced by survivor readiness, clinical context, and resource availability.
This finding emerged from semistructured interviews with 12 medical team members involved in oncology care
Lack of access to PA resources was the most common barrier reported by medical team members (9/12)
These factors represent opportunity and capability constraints on clinician-level PA promotion
Methods
The study used the COM-B framework to map multilevel barriers and facilitators to PA in cardio-oncology care from both survivor and provider perspectives.
A descriptive qualitative study design was employed with 12 cancer survivors and 12 medical team members
Semistructured interviews explored experiences, perceptions, and practices related to PA across the cancer care continuum
Rapid qualitative analysis was used to identify themes, which were then mapped to COM-B domains (Capability, Opportunity, Motivation-Behavior)
What This Means
This research suggests that most cancer survivors in cardio-oncology care are not meeting recommended levels of physical activity, with only about 4 in 10 survivors doing so. Using in-depth interviews with both cancer survivors and members of their medical teams, researchers found that multiple interconnected factors influence whether survivors engage in physical activity. Physical limitations were a universal challenge, but nearly all survivors also pointed to their existing activity habits and social support networks as key motivators and enablers of continued exercise.
The study found that both survivors and medical team members valued physical activity highly and believed it could improve health outcomes, yet sustained participation remained difficult. Survivors faced fluctuating symptoms and safety concerns, while healthcare providers were constrained by limited resources, uncertainty about clinical appropriateness, and variability in how ready individual patients were to start or maintain exercise programs. Lack of access to physical activity resources was the most commonly reported barrier among medical team members.
This research suggests that simply telling cancer survivors to exercise more is unlikely to be effective on its own. Instead, interventions may need to be flexible and tailored to individual survivors' changing physical conditions, leverage social support systems, improve access to appropriate exercise resources, and support clinicians in having better conversations about physical activity throughout the entire cancer care journey. These findings point to the need for a more coordinated, patient-centered approach to promoting exercise in cancer survivorship care.
Tetrick M, Addison D, Singh R, St George S, Pavia V, Gogineni A, et al.. (2026). Assessment of Physical Activity Engagement and Promotion Among Cancer Survivors in Cardio-Oncology Care: Qualitative Study.. JMIR cancer. https://doi.org/10.2196/104332