Physical activity was negatively associated with perceived stress, which in turn was positively associated with oral symptoms, suggesting the association between physical activity and oral health is mediated primarily through perceived stress rather than a direct effect.
Key Findings
Results
Nearly half of university students had insufficient physical activity and over a third reported high or excessive stress.
Total sample size was 1578 university students in mainland China.
47.7% of students had insufficient physical activity as measured by the International Physical Activity Questionnaire Short Form.
38.7% reported high or excessive stress as measured by the 14-item Perceived Stress Scale.
This was a cross-sectional survey design.
Results
Insufficient physical activity and elevated stress levels were each independently associated with increased risk of gingival bleeding and oral ulcers.
Associations were identified using multivariable logistic regression analysis.
Both insufficient physical activity and elevated stress reached statistical significance at P < .05.
Oral health was evaluated through self-reported indicators including gingival bleeding, toothache, and oral ulcer.
Toothache was among the outcomes assessed but was not specifically highlighted as significantly associated in the abstract findings.
Results
Physical activity was negatively associated with perceived stress in structural equation modeling.
Standardized coefficient for the physical activity to perceived stress path was -0.360.
This association was statistically significant at P < .05.
This suggests that higher levels of physical activity were associated with lower perceived stress.
Results
Perceived stress was positively associated with self-reported oral symptoms in structural equation modeling.
Standardized coefficient for the perceived stress to oral symptoms path was 0.411.
This association was statistically significant at P < .05.
This was the strongest direct path in the structural equation model linking the measured variables to oral health outcomes.
Results
The direct association between physical activity and oral symptoms was not statistically significant, indicating stress mediated the relationship.
Standardized coefficient for the direct physical activity to oral symptoms path was -0.009.
This direct path was not statistically significant (P = .765).
Structural equation modeling showed the association between physical activity and oral symptoms was mediated primarily through perceived stress rather than a direct effect.
This mediation finding was a key result distinguishing direct from indirect pathways.
What This Means
This research suggests that among Chinese university students, there is a meaningful chain of association linking physical activity, mental stress, and oral health problems. Nearly half of the 1578 students surveyed were not getting enough physical activity, and more than a third were experiencing high levels of stress. Both low physical activity and high stress were linked to a greater likelihood of problems like gum bleeding and mouth ulcers.
Importantly, the study found that physical activity does not seem to directly improve oral health on its own. Instead, the benefit appears to work indirectly: students who are more physically active tend to experience less psychological stress, and lower stress in turn is associated with fewer oral health complaints. This mediation finding helps explain the mechanism connecting lifestyle behaviors to oral health outcomes.
This research suggests that universities looking to improve students' oral health should consider addressing both exercise habits and mental health support together, rather than focusing narrowly on dental hygiene alone. Integrated programs that promote regular physical activity and reduce stress could have broader benefits for student well-being, including their oral health. Because this was a cross-sectional study (a snapshot in time), it cannot prove that changing physical activity or stress levels will directly cause oral health to improve, but it points to stress reduction as a potentially important pathway worth exploring.
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Li Q, Chen Z, Sun C, Lin S, Yang X, Li J. (2026). Association among physical activity, stress and oral health among university students: A cross-sectional study.. Medicine. https://doi.org/10.1097/MD.0000000000050759