Cardiovascular

Association Between Immigration Status and the Intensity of Acute Stroke Care in Ontario, Canada: A Retrospective Study.

TL;DR

Immigrant ischemic stroke patients have similar ICU admission rates but longer ICU stays compared to long-term residents, with adjusted risk ratios of 1.30 for longer ICU stays persisting even among those who did not receive reperfusion treatments.

Key Findings

Immigrants with ischemic stroke had similar odds of ICU admission compared to long-term residents despite differences in patient characteristics.

  • ICU admission rates were 18.2% for immigrants vs 19.7% for long-term residents
  • Adjusted odds ratio for ICU admission was 0.97 (95% CI 0.91–1.04), indicating no statistically significant difference
  • Study included 85,507 patients hospitalized for ischemic stroke in Ontario, Canada between April 1, 2014, and March 30, 2023
  • 12.9% of the cohort were immigrants, defined as people born outside Canada who arrived after 1985

Immigrant ischemic stroke patients had significantly longer ICU stays than long-term residents.

  • Mean ICU stay was 5.6 ± 18.5 days for immigrants vs 3.8 ± 7.7 days for long-term residents
  • Adjusted risk ratio (aRR) for longer ICU stay was 1.30 (95% CI 1.13–1.48)
  • The association remained significant among patients who did not receive reperfusion treatments (aRR 1.27; 95% CI 1.09–1.49)
  • Negative binomial models were used to calculate adjusted risk ratios of longer ICU stays

Immigrants were younger and had lower stroke severity but higher rates of life-sustaining treatments compared to long-term residents.

  • Median age was 69 years for immigrants vs 76 years for long-term residents (standardized difference = 0.38)
  • Immigrants had lower stroke severity and lower rates of reperfusion treatments (thrombolysis and thrombectomy)
  • Immigrants had higher rates of life-sustaining treatments including ventilatory support and feeding tube insertion
  • 45% of the overall cohort was female

The association between immigration status and longer ICU stays did not vary by whether a hospital cared for a higher-than-median proportion of immigrants.

  • Analyses were conducted across all hospitals in Ontario
  • Hospital-level proportion of immigrant patients did not modify the association between immigration status and ICU length of stay
  • This finding suggests the disparity is not explained by concentration of immigrants at specific hospital types

Certain immigrant subgroups had particularly longer ICU stays compared to long-term residents.

  • Immigrants who came as refugees had longer ICU stays than long-term residents
  • Immigrants from Africa, East Asia, and the Middle East had longer ICU stays than long-term residents
  • These subgroup differences were identified within the broader immigrant cohort

The study was a large population-based retrospective cohort study using Ontario health administrative data over nearly a decade.

  • Study period was April 1, 2014, to March 30, 2023
  • Total cohort included 85,507 adults hospitalized for ischemic stroke
  • Immigration status was defined as being born outside Canada and arriving after 1985
  • Logistic regression models were used for ICU admission odds ratios and negative binomial models for length of stay risk ratios

The authors suggest that higher rates of life-saving treatments among immigrants may partly explain their longer ICU stays, but long-term functional outcomes remain unstudied.

  • The authors note that 'the longer ICU stays among immigrant stroke patients may in part be driven by higher rates of life-saving treatments'
  • The impact of these differences on long-term functional outcomes 'remains to be studied'
  • The findings highlight a need for future research into downstream outcomes for immigrant stroke patients

What This Means

This research examined whether being an immigrant affects the type and intensity of hospital care received after a stroke in Ontario, Canada. Using data from over 85,000 stroke patients treated between 2014 and 2023, the study found that immigrants were just as likely as long-term Canadian residents to be admitted to the intensive care unit (ICU) following a stroke. However, once admitted, immigrants stayed in the ICU significantly longer — on average 5.6 days compared to 3.8 days for long-term residents, even after accounting for differences in age, stroke severity, and other factors. Interestingly, immigrants were younger and had less severe strokes on average, yet they received more life-sustaining interventions such as mechanical ventilation and feeding tubes. This pattern of longer ICU stays persisted even among patients who did not receive clot-busting or clot-removal treatments, and it was not explained by whether a hospital served many immigrants or few. Certain groups — including refugees and immigrants from Africa, East Asia, and the Middle East — had especially long ICU stays compared to long-term residents. This research suggests that immigrant stroke patients experience a distinct pattern of acute hospital care that does not simply reflect differences in stroke severity or access to advanced treatments. The reasons for longer ICU stays are not fully understood — they may relate to differences in goals-of-care conversations, language barriers, cultural factors, or end-of-life decision-making. The study highlights an important gap: it is not yet known whether the longer ICU stays translate into better, worse, or similar long-term functional recovery for immigrant patients, which is a critical question for future research.

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Citation

Kuczynski A, Yu A, Fowler R, Hong Z, Odugbemi T, Fang J, et al.. (2026). Association Between Immigration Status and the Intensity of Acute Stroke Care in Ontario, Canada: A Retrospective Study.. Neurology. https://doi.org/10.1212/WNL.0000000000218543