Cardiovascular

Association between meteorological factors and blood pressure variability in northern Guizhou, China.

TL;DR

In this hospital-based population, city-level relative humidity and shortwave radiation were associated with daily mean blood pressure variability, with higher relative humidity and lower shortwave solar radiation positively associated with greater BPV over a maximum lag of 14 days.

Key Findings

Higher relative humidity was positively associated with greater blood pressure variability over a maximum lag of 14 days.

  • The study used distributed lag non-linear models (DLNMs) to estimate associations between meteorological exposures and BPV.
  • The maximum lag period examined was 14 days.
  • Both systolic and diastolic BPV indices were calculated from ambulatory blood pressure monitoring data.
  • The associations are described as ecological associations rather than evidence of causal effects.

Lower shortwave solar radiation was positively associated with greater blood pressure variability over a maximum lag of 14 days.

  • Daily shortwave radiation was one of three meteorological variables examined alongside relative humidity and temperature.
  • The association was estimated using DLNMs across a 14-day lag period.
  • Both systolic and diastolic BPV indices were included in the analysis.
  • Results reflect city-level exposure data rather than individual-level measurements.

Ambulatory blood pressure monitoring data from 4,355 patients in northern Guizhou, China were used to calculate blood pressure variability indices.

  • The sample consisted of 4,355 patients with hypertension.
  • The study was hospital-based and located in northern Guizhou, China.
  • Both systolic and diastolic BPV indices were calculated from the ambulatory monitoring data.
  • Daily meteorological variables included relative humidity, shortwave radiation, and temperature.

Exploratory subgroup analyses suggested larger associations in certain population subgroups stratified by age, sex, smoking status, and alcohol consumption.

  • Subgroup stratification was conducted by age, sex, smoking status, and alcohol consumption.
  • The authors cautioned that these findings were based on aggregated data and involved multiple comparisons.
  • The subgroup findings are described as exploratory rather than confirmatory.
  • These results should not be interpreted as confirmed individual susceptibility.

The study authors characterized their findings as ecological associations rather than evidence of causal effects or confirmed individual susceptibility.

  • Exposure assessment was conducted at the city level rather than the individual level.
  • The authors called for validation in multicenter studies incorporating individual-level exposure assessment.
  • The hospital-based study design limits generalizability of the findings.
  • Most previous studies in this area focused on air pollution effects on resting blood pressure rather than BPV.

What This Means

This research suggests that weather conditions — specifically humidity and sunlight — may be linked to how much a person's blood pressure fluctuates throughout the day, a measure known as blood pressure variability (BPV). Using data from 4,355 hypertension patients in northern Guizhou, China, the researchers found that on days with higher humidity or less sunlight, patients tended to have greater swings in both their systolic (top number) and diastolic (bottom number) blood pressure readings. These associations were detected looking back up to 14 days prior to measurement, using a statistical technique that can capture delayed and non-linear effects of environmental exposures. The study also found that some groups — including people of different ages, sexes, smoking habits, and alcohol use — may show stronger associations, though the researchers cautioned that these subgroup results are preliminary and should be interpreted with care due to the nature of the data and the number of comparisons made. Importantly, the authors emphasize that these are ecological-level findings, meaning they are based on city-wide weather data rather than measurements taken at each individual's location, which limits the conclusions that can be drawn about any one person's risk. This research matters because blood pressure variability — not just average blood pressure — is increasingly recognized as a risk factor for cardiovascular disease, stroke, and other serious conditions. Understanding how everyday environmental factors like weather might influence BPV could help explain some of the seasonal and regional differences seen in cardiovascular events. However, the authors stress that larger, multicenter studies with more precise individual-level exposure data are needed before these findings can inform clinical practice or public health recommendations.

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Citation

Tang Y, Lei Y, Hu X, Zhang Y, Yao Y, Chen X, et al.. (2026). Association between meteorological factors and blood pressure variability in northern Guizhou, China.. Frontiers in public health. https://doi.org/10.3389/fpubh.2026.1888902