Associations Between Comorbidities, Medication Use and Dental Outcomes in Clinical Practice in Hail Dental Centre in Saudi Arabia: A Retrospective Study.
Alotaibi A, Bakitian F, et al. • Oral health & preventive dentistry • 2026
This retrospective study of 383 dental patients in Saudi Arabia found high prevalences of diabetes (53.5%), hypertension (49.6%), and hypothyroidism (23.0%), with significant associations between diabetes and active dental caries and between hypertension and increased dental pain.
Key Findings
Results
The study population had a mean age of 51.5 years with a female predominance.
Mean age was 51.5 years (SD = 16.5)
65% of the 383 dental patients were female
The study was conducted at Hail Dental Centre in Saudi Arabia
Data included demographic information, medical history, medication profiles, and dental health parameters
Results
Diabetes was the most prevalent medical condition among dental patients in the study sample.
Prevalence of diabetes was 53.5%
Hypertension was the second most common condition at 49.6%
Hypothyroidism was present in 23.0% of patients
The sample size was 383 dental patients
Results
Polypharmacy occurred in a minority of patients, and commonly used medications included antihypertensives, antidiabetics, and analgesics.
Polypharmacy, defined as use of 5 or more medications, occurred in 8.4% of patients
Commonly used medication classes included antihypertensives, antidiabetics, and analgesics
Medication profiles were part of the retrospective data analysed
Results
The mean number of active dental caries was 1.37 per patient across the study sample.
Mean number of active dental caries was 1.37 per patient
Dental health parameters were analysed as part of the retrospective data
Active caries count was used as a dental health outcome measure
Results
Diabetes was significantly associated with the number of active dental caries in the study population.
A significant association was observed between diabetes and the number of active caries
Diabetes prevalence in the sample was 53.5%
The finding suggests diabetes as a risk factor for caries in this dental patient population
Associations were explored using descriptive statistics
Results
Hypertension was significantly associated with increased dental pain among the study patients.
Hypertension was associated with increased dental pain
Hypertension prevalence in the sample was 49.6%
Dental pain was assessed as a dental health outcome measure
The association was identified through analysis of medical conditions and dental health outcomes
Conclusions
The authors concluded that comprehensive medical history assessment is important in dental practice for medically compromised patients.
Findings highlight the high prevalence of medical conditions and medication use among dental patients
Understanding these patterns can inform treatment planning, risk assessment, and preventive strategies
The study was retrospective in design with a sample of 383 patients
Results emphasise the importance of understanding comorbidities and medication use for safe dental care
Alotaibi A, Bakitian F, Alshammari H, Alqhtani A, Elboraey M, Fayad M, et al.. (2026). Associations Between Comorbidities, Medication Use and Dental Outcomes in Clinical Practice in Hail Dental Centre in Saudi Arabia: A Retrospective Study.. Oral health & preventive dentistry. https://doi.org/10.3290/j.ohpd.c_2615