Body composition and muscle health changes after providing vascular imaging results in older adults: secondary analysis of a randomised controlled trial.
Dalla Via J, Radavelli-Bagatini S, et al. • Aging clinical and experimental research • 2026
Providing abdominal aortic calcification (AAC) results with healthy lifestyle education did not improve body composition or muscle health in older adults compared to education alone, though exploratory analyses suggested those with evidence of AAC had greater reductions in fat mass and visceral adipose tissue.
Key Findings
Results
Provision of AAC results combined with lifestyle education provided no benefits to body composition, grip strength, or physical function compared to education alone.
240 Australian community-dwelling older men and women were randomised (mean ± SD age 68 ± 5 years; 58% female; 57.1% with evidence of AAC)
Participants were randomised to AAC + Ed (n = 121) or Control + Ed (n = 119)
The trial was a 12-week parallel-group randomised controlled trial
Linear mixed models were used to compare between-group changes in body composition (dual-energy X-ray absorptiometry), grip strength, and subjective physical function
226 (94%) participants completed the trial
Results
Within the AAC + Ed group, participants with evidence of AAC at baseline had greater declines in fat mass compared to those without evidence of AAC.
Net difference in change in fat mass was -0.6 kg (95% CI: -1.0, -0.1 kg), p = 0.016
This was an exploratory analysis within the AAC + Ed group only
The comparison was between those with and without evidence of AAC at baseline
Results
Within the AAC + Ed group, participants with evidence of AAC at baseline had greater reductions in visceral adipose tissue compared to those without evidence of AAC.
Net difference in change in visceral adipose tissue was -31 g (95% CI: -61, -1 g), p = 0.044
This was an exploratory analysis within the AAC + Ed group only
The authors noted these findings require further investigation
Methods
The study population had a high prevalence of abdominal aortic calcification at baseline.
57.1% of the 240 participants had evidence of AAC at baseline
Participants were community-dwelling older adults with a mean age of 68 ± 5 years
The sample was 58% female
Background
Vascular imaging result provision has been investigated to prompt healthy lifestyle behaviour changes, but effects on body composition and muscle health were previously unknown.
This study was a secondary analysis of a 12-week parallel-group RCT
The intervention involved providing AAC results obtained via dual-energy X-ray absorptiometry alongside healthy lifestyle education
Body composition, grip strength, and subjective physical function were assessed as outcomes
Dalla Via J, Radavelli-Bagatini S, Sim M, Gebre A, Bondonno C, Zhu K, et al.. (2026). Body composition and muscle health changes after providing vascular imaging results in older adults: secondary analysis of a randomised controlled trial.. Aging clinical and experimental research. https://doi.org/10.1007/s40520-026-03335-1