Body Composition

Cardiometabolic index predicts postoperative atrial fibrillation after isolated CABG: ROC-based comparison with BMI and visceral adiposity indices.

TL;DR

The cardiometabolic index (CMI) emerged as a significant predictor for postoperative atrial fibrillation following isolated CABG (OR: 4.054, 95% CI: 1.77-9.23; p=0.010), demonstrating superior predictive performance compared to BMI and visceral adiposity index while showing comparable diagnostic value to lipid accumulation product and body roundness index.

Key Findings

Cardiometabolic index (CMI) was a significant independent predictor of postoperative atrial fibrillation after isolated CABG.

  • CMI showed an odds ratio of 4.054 (95% CI: 1.77-9.23; p=0.010) for postoperative atrial fibrillation development.
  • CMI is described as 'a composite measure of visceral adiposity and metabolic dysfunction.'
  • CMI demonstrated superior predictive performance compared to body mass index (BMI) and visceral adiposity index (VAI).
  • CMI showed comparable diagnostic value to the lipid accumulation product (LAP) and body roundness index (BRI).

Univariate analysis identified diabetes mellitus, high EuroSCORE II, and extended cardiopulmonary bypass duration as significantly associated with postoperative atrial fibrillation.

  • These factors were identified through univariate analysis as significant associations with postoperative atrial fibrillation occurrence.
  • EuroSCORE II is a cardiac surgical risk scoring system used for preoperative risk stratification.
  • Extended cardiopulmonary bypass duration was identified as a procedural risk factor for postoperative atrial fibrillation.

Visceral adiposity indices derived from anthropometric and biochemical parameters demonstrated substantial predictive value for postoperative atrial fibrillation.

  • Indices were derived from anthropometric measurements and biochemical parameters collected during the preoperative period.
  • Discriminative abilities were compared using receiver operating characteristic (ROC) curve analysis and area under the curve (AUC) values.
  • Multiple visceral adiposity indices were evaluated including CMI, BMI, VAI, lipid accumulation product (LAP), and body roundness index (BRI).
  • The study notes that 'the assessment of visceral adipose tissue activity has gained significance in cardiac risk stratification.'

The study identified cutoff values for visceral adiposity indices in predicting postoperative atrial fibrillation, but cautioned that these require validation.

  • The authors stated that 'the suggested cutoff values should be interpreted cautiously.'
  • Validation is recommended 'in diverse patient populations and larger cohorts prior to clinical implementation.'
  • The study is described as 'exploratory' in nature, limiting the generalizability of the cutoff values.
  • ROC-based analysis was used to derive the cutoff values for each index examined.

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Citation

Kahraman E, Cetin &. (2026). Cardiometabolic index predicts postoperative atrial fibrillation after isolated CABG: ROC-based comparison with BMI and visceral adiposity indices.. Biomolecules & biomedicine. https://doi.org/10.17305/bb.2026.13693