Cardiovascular

Cardiometabolic risk profile and associated factors among adults with type 2 diabetes in a primary health care clinics in North Central Nigeria.

TL;DR

Adults with type 2 diabetes attending primary health care clinics in North Central Nigeria had a high burden of cardiometabolic abnormalities, with 84.8% having at least one abnormal component, highlighting the need for integrated diabetes management strategies.

Key Findings

The large majority of adults with type 2 diabetes in primary health care settings had at least one cardiometabolic abnormality.

  • 84.8% of participants had at least one cardiometabolic abnormality
  • Cardiometabolic abnormality was defined as the presence of at least one of: poor glycaemic control, dyslipidaemia, or renal impairment
  • The mean cardiometabolic risk score was 1.87 ± 1.05
  • Study was conducted among 120 systematically recruited adults aged ≥ 30 years with T2DM at government-owned PHC facilities in Makurdi, Benue State, Nigeria

Poor glycaemic control was the most prevalent individual cardiometabolic abnormality among study participants.

  • 65.8% of participants had poor glycaemic control
  • Longer diabetes duration independently predicted poor glycaemic control (p < 0.05)
  • The mean diabetes duration among participants was 4 ± 3.2 years
  • The mean age of participants was 56 ± 10.8 years, with females comprising 61.7%

Dyslipidaemia was nearly as prevalent as poor glycaemic control among adults with type 2 diabetes in this primary care setting.

  • 65.0% of participants had dyslipidaemia
  • Lipid profile was assessed as part of the laboratory analyses
  • The study authors note that evidence on comprehensive metabolic risk profiling beyond glycaemic control remains limited in Nigeria
  • These findings support the need for routine lipid assessment in resource-limited settings

Renal impairment was present in approximately one-third of participants with type 2 diabetes attending primary health care clinics.

  • 29.2% of participants had renal impairment
  • Renal impairment was determined using estimated glomerular filtration rate (eGFR) based on standard clinical thresholds
  • Renal function was assessed as part of the laboratory analyses alongside glycaemic status and lipid profile
  • The study authors highlight these findings as supporting the need for routine renal function assessment in resource-limited settings

Longer diabetes duration was independently associated with poor glycaemic control, while other factors were not independently associated with adverse cardiometabolic outcomes.

  • Longer diabetes duration independently predicted poor glycaemic control (p < 0.05)
  • Other factors assessed were not independently associated with adverse cardiometabolic outcomes at the p < 0.05 threshold
  • Data were analysed using descriptive statistics and logistic regression
  • Socio-demographic and clinical data were obtained using structured questionnaires and medical records

The study population was predominantly female and middle-aged, reflecting the demographics of type 2 diabetes patients attending primary health care facilities in this region.

  • Females comprised 61.7% of participants
  • The mean age was 56 ± 10.8 years
  • Participants were aged ≥ 30 years
  • The mean diabetes duration was 4 ± 3.2 years
  • 120 eligible adults were systematically recruited from government-owned PHC facilities in Makurdi, Benue State, Nigeria

What This Means

This research examined the heart and metabolic health of 120 adults with type 2 diabetes who were receiving care at government-run primary health clinics in Makurdi, Nigeria. Researchers measured blood sugar control, blood fat levels (lipids), and kidney function to build a comprehensive picture of cardiovascular and metabolic risk. The study found that the vast majority of patients — nearly 85% — had at least one serious health abnormality beyond just diabetes itself. Poor blood sugar control affected about two-thirds of patients, abnormal blood fat levels also affected about two-thirds, and nearly one-third showed signs of reduced kidney function. On average, patients had almost two of these problems simultaneously. This research suggests that diabetes care in these primary health care settings is falling short of addressing the full range of health risks that come with type 2 diabetes. The fact that having diabetes for a longer period of time was linked to worse blood sugar control points to the challenges of managing this chronic disease over time in resource-limited settings. Many patients appeared to have serious cardiovascular and kidney risks that may not be routinely detected or treated. The practical implication of these findings is that diabetes management in primary health care clinics in Nigeria — and potentially similar settings across the region — needs to go beyond just monitoring blood sugar. This research suggests that routine testing of blood fat levels and kidney function should be integrated into standard diabetes care, even in resource-limited environments, because the burden of these additional health problems appears to be substantial.

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Citation

Okonkwo I, Idoh M, Agbo E, Okafor E. (2026). Cardiometabolic risk profile and associated factors among adults with type 2 diabetes in a primary health care clinics in North Central Nigeria.. African journal of primary health care &amp; family medicine. https://doi.org/10.4102/phcfm.v18i1.5461