Cardiovascular

Cardiovascular risk profile and treatment patterns in patients with type 2 diabetes in specialized cardiology outpatient care in Colombia: A retrospective cross-sectional study.

TL;DR

In this single-center Colombian cohort of 138 adults with T2DM in specialized cardiology care, HbA1c >7% was common (70.3%) and was associated with higher total cholesterol and with the presence of echocardiographic abnormalities, while the lower SGLT2 inhibitor use seen with HbA1c >7% did not persist after adjustment.

Key Findings

Most patients with T2DM in this specialized cardiology clinic had HbA1c above 7%.

  • Single-center, retrospective cross-sectional study of 138 adults with confirmed T2DM in Barranquilla, Colombia, during 2023 to 2024.
  • 70.3% had HbA1c >7%, using the most recent value at the latest outpatient visit.
  • Mean age was 67.3 ± 11.5 years and 71.7% were male.

Patients with HbA1c >7% were older than those with HbA1c ≤7%.

  • Mean age was 68.6 ± 11.6 vs 64.2 ± 10.9 years (P = .034).

Patients with HbA1c >7% had higher total cholesterol and LDL cholesterol in univariable analysis.

  • Total cholesterol was 203.5 ± 48.1 vs 181.7 ± 42.8 mg/dL (P = .010).
  • LDL cholesterol was 124.9 ± 36.1 vs 106.0 ± 39.1 mg/dL (P = .010).

Cerebrovascular disease was present only in patients with HbA1c >7%.

  • Cerebrovascular disease occurred in 11.3% of patients with HbA1c >7% and in none of those with HbA1c ≤7% (P = .034).

Absence of prespecified echocardiographic abnormalities was less frequent in patients with HbA1c >7%.

  • 15.5% vs 34.1% had no prespecified echocardiographic abnormalities (P = .014).

SGLT2 inhibitor use was low overall and was more frequent in patients with HbA1c ≤7% in unadjusted analysis.

  • SGLT2 inhibitor use was documented in 16.7% overall.
  • Use was 26.8% with HbA1c ≤7% vs 12.4% with HbA1c >7% (P = .037).

In the exploratory multivariable model, higher total cholesterol was independently associated with HbA1c >7%.

  • Adjusted OR per 10 mg/dL = 1.10 (95% CI, 1.01-1.20; P = .033).
  • Model used logistic regression with the enter method and was described as exploratory.

In the multivariable model, absence of prespecified echocardiographic abnormalities was inversely associated with HbA1c >7%.

  • Adjusted OR = 0.36 (95% CI, 0.15-0.88; P = .026).

The association between SGLT2 inhibitor use and HbA1c control was not significant after adjustment.

  • Adjusted OR = 0.56 (95% CI, 0.20-1.58; P = .274).

The authors conclude that the cross-sectional findings support integrated cardiometabolic assessment in specialized outpatient care.

  • Real-world data integrating cardiovascular comorbidities, metabolic characteristics, echocardiography, and treatment patterns are limited in Colombia.
  • The design is cross-sectional, single-center, and retrospective.

What This Means

This study looked at the medical records of 138 adults with type 2 diabetes who were seen at a specialized heart clinic in Barranquilla, Colombia, in 2023–2024. About 7 in 10 patients had blood sugar control (HbA1c) above the common 7% target. Those with poorer control tended to be older, had higher total and LDL cholesterol, and were more likely to have heart-structure or function abnormalities on echocardiograms. Strokes or other cerebrovascular disease were found only in the poorer-control group. Only about 1 in 6 patients was prescribed an SGLT2 inhibitor, a class of diabetes drugs with known heart benefits. Use was higher among patients with better-controlled blood sugar, but this difference was no longer statistically significant once other factors were accounted for. After adjustment, higher total cholesterol was linked to a greater chance of HbA1c above 7%, and having no echocardiographic abnormalities was linked to a lower chance. This research suggests that blood sugar, cholesterol, and heart findings often go together in people with diabetes seen by cardiologists, supporting a combined approach to assessment. Because the study was small, from one center, based on a single point in time, and the regression was exploratory, it cannot show cause and effect or that these results apply to all patients in Colombia.

Have a question about this study?

Citation

Suarez Maestre L, Hoyos Montaño I, Rúa Osorio Z, Renowitzky Zabarain C, Dominguez Vargas A, González-Torres H. (2026). Cardiovascular risk profile and treatment patterns in patients with type 2 diabetes in specialized cardiology outpatient care in Colombia: A retrospective cross-sectional study.. Medicine. https://doi.org/10.1097/MD.0000000000051307