Cardiovascular

Case 351: Thalamic Dementia Secondary to Dural Arteriovenous Fistula.

TL;DR

A 76-year-old man with subacute confusion, falls, and urinary incontinence that progressed to drowsiness, facial twitching, and seizures was worked up with CT, CT angiography, MRI, and digital subtraction angiography for a suspected thalamic dementia secondary to a dural arteriovenous fistula; the abstract describes the presentation and workup but does not report the imaging findings or final diagnosis.

Key Findings

A 76-year-old man with diabetes, hypertension, and dilated cardiomyopathy developed subacute cognitive decline, repeated falls, and urinary incontinence over 3-4 months, with worsening over 2 weeks.

  • Symptoms included confusion, memory lapses (e.g., forgetting his mother's recent death), and functional cognitive problems such as being unable to dose his insulin with meals.
  • His partner reported no prior memory or movement disorders.
  • Symptoms worsened over a 2-week period, leading to emergency room presentation.

At presentation the neurologic examination was largely normal apart from disorientation to date, and common alternative causes were not found.

  • The patient was awake and alert, oriented to name and location but not date.
  • Full neurologic examination of motor, sensory, and cranial nerve function was normal.
  • There were no signs of meningism, no fever or leukocytosis, and no recent travel.
  • Serum electrolytes and thiamine levels were normal, and there was no history of alcohol or drug abuse.

Initial imaging included noncontrast head CT, which prompted multiphasic CT angiography with parenchymal phase imaging and admission for observation with serial noncontrast head CT.

  • The abstract states the noncontrast CT results prompted further imaging but does not report the specific findings.
  • Serial noncontrast CT was used for monitoring during admission.

The patient's condition deteriorated in hospital, with new facial twitching, increased drowsiness, and seizure episodes.

  • Worsening symptoms led to evaluation with noncontrast brain MRI.
  • Digital subtraction angiography with external carotid artery and internal carotid artery contrast injections followed.

The case title identifies the diagnosis as thalamic dementia secondary to a dural arteriovenous fistula, but the abstract does not give the imaging findings or treatment outcome.

  • The abstract ends with the planned MRI and digital subtraction angiography.
  • No quantitative data, imaging descriptions, or outcomes are given in the abstract.

What This Means

This case report describes an older man who developed confusion, memory problems, falls, and loss of bladder control over several months. These problems became worse over two weeks. Routine tests, including blood work, thiamine levels, and a neurological exam, did not point to an obvious cause such as infection, electrolyte problems, or alcohol or drug use. He was admitted for monitoring and had a series of brain scans, including CT, CT angiography, and MRI. While in hospital he developed facial twitching, more drowsiness, and seizures, and he then underwent a detailed blood vessel imaging study called digital subtraction angiography. The title indicates the cause was an abnormal connection between an artery and a vein in the brain's covering (a dural arteriovenous fistula) that affected deep brain structures called the thalami and produced a dementia-like illness. This research suggests that a rapidly progressing dementia-like condition with seizures may sometimes come from a blood vessel abnormality rather than a degenerative brain disease. The abstract does not include the scan findings, treatment, or outcome, so those details cannot be drawn from it.

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Citation

Deen S, Khalili B, Semalti K, Chen M, Dua S, Ansari S. (2026). Case 351: Thalamic Dementia Secondary to Dural Arteriovenous Fistula.. Radiology. https://doi.org/10.1148/radiol.252189