A case of cerebral air embolism secondary to oesophageal-pulmonary vein fistula caused by fish bone ingestion is reported, underscoring the diagnostic importance of multimodal imaging and procedural planning for safe management.
Key Findings
Background
Fish bone ingestion caused an oesophageal-pulmonary vein fistula resulting in cerebral air embolism, a rare complication.
The patient was a man in his 80s who presented after sudden collapse following oesophageal discomfort from fish bone ingestion the previous day.
The case was managed at a tertiary emergency centre.
Cerebral air embolism as a secondary complication of fish bone ingestion is described as 'exceedingly rare'.
Results
Head CT identified punctate hypodense foci in the right frontal white matter consistent with cerebral air.
CT perfusion showed decreased cerebral blood flow with delayed transit time in the affected region.
These findings were identified on initial presentation imaging.
Multimodal imaging including both non-contrast CT and CT perfusion contributed to the diagnosis.
Results
Chest CT demonstrated a fish bone impacted in the distal oesophagus with air bubbles visible in the pulmonary vein.
The presence of air bubbles in the pulmonary vein on chest CT provided evidence of the oesophageal-pulmonary vein fistula.
The fish bone was located in the distal oesophagus.
This imaging finding linked the oesophageal perforation to the cerebral air embolism via systemic arterial air entry.
Results
Urgent endoscopy confirmed the fish bone, which was removed under general anaesthesia with mucosal clipping performed for haemostasis.
General anaesthesia was used for procedural safety during fish bone removal.
Mucosal clipping was employed as the haemostatic technique following fish bone extraction.
The procedural approach reflects considerations for safe management in the context of concurrent cerebral air embolism.
Results
MRI performed on day six demonstrated cortical infarctions in the right hemisphere.
The infarctions were identified six days after the initial presentation.
Infarctions were located in the cortex of the right hemisphere, consistent with the initial CT findings of right frontal involvement.
The MRI findings confirmed ischaemic injury resulting from the cerebral air embolism.
Conclusions
The case underscores the diagnostic importance of multimodal imaging for cerebral air embolism caused by oesophageal perforation.
Modalities used included head CT, CT perfusion, chest CT, and MRI.
The combination of imaging modalities allowed identification of both the source (oesophageal fistula) and the consequence (cerebral air embolism and subsequent infarction).
The authors highlight procedural planning as essential for safe management in this rare complication.
What This Means
This research describes a case of an elderly man who swallowed a fish bone and developed a very rare and life-threatening complication. The fish bone pierced through the wall of the oesophagus (the tube connecting the mouth to the stomach) and created an abnormal connection with a pulmonary vein (a blood vessel carrying blood from the lungs to the heart). This allowed air to enter the bloodstream and travel to the brain, causing what is known as a cerebral air embolism — air bubbles blocking blood flow in the brain — which led to a stroke.
Doctors used multiple types of scans to piece together what had happened: a standard CT scan of the head showed air in the brain tissue, a CT perfusion scan showed reduced blood flow, and a chest CT revealed both the fish bone in the oesophagus and air bubbles in the pulmonary vein. The fish bone was removed by endoscopy (a camera passed down the throat) while the patient was under general anaesthesia, with clips applied to seal the wound. An MRI scan six days later confirmed that areas of the brain had suffered infarction (tissue death from lack of blood flow) on the right side.
This research suggests that when a patient presents with sudden neurological symptoms after fish bone ingestion, doctors should consider the rare possibility of cerebral air embolism caused by an oesophageal fistula. Using a combination of imaging tools is important to identify both the cause and the extent of brain injury, and careful procedural planning is needed to safely remove the foreign body while minimising further risk to the patient.
Kawai R, Miyashita F, Maki Y, Yoshimoto Y, Hiramine T, Okada T, et al.. (2026). Cerebral air embolism from oesophageal-pulmonary vein fistula induced by fish bone ingestion.. BMJ case reports. https://doi.org/10.1136/bcr-2026-272690