A nurse-led telehealth PrEP clinic ('TelePrEP') with free multi-modal testing pathway was found to be feasible in overcoming issues of accessibility for key population groups including overseas-born MSM, achieving high overall attendance rates, high adherence to guideline-indicated laboratory monitoring, and rapid linkage to treatment for clients with HIV identified on screening.
Key Findings
Results
The TelePrEP client population was predominantly cisgender male, non-Medicare, and overseas-born.
A total of 472 clients were reviewed in the retrospective analysis.
99% of clients were cisgender male.
77% of clients were non-Medicare status.
86% of clients were overseas-born.
Results
There was no significant difference in appointment attendance rates between the three screening pathways (MyCheck, a[TEST], and Xpress).
Three distinct screening pathways were compared: MyCheck, a[TEST], and Xpress.
The analysis found no statistically significant difference in attendance rates across the three pathways.
This finding applied across the full sample of 472 clients reviewed.
Results
The majority of TelePrEP appointments referred through the MyCheck pathway resulted in PrEP continuation.
82% of appointments referred through MyCheck resulted in PrEP continuation.
This suggests MyCheck referrals predominantly represented clients already established on PrEP.
Results
Follow-up screening attendance rates were low overall, with variation by screening pathway.
Overall, 36% of clients attended follow-up screening.
The highest rate of follow-up was among clients referred through a[TEST] at 44%.
The lowest rate of follow-up was among clients referred through Xpress at 22%.
Results
Non-Medicare clients attended follow-up screening at a higher rate than Medicare clients.
38% of non-Medicare clients attended follow-up screening.
27% of Medicare clients attended follow-up screening.
Non-Medicare clients comprised 77% of the total client population reviewed.
Results
Adherence to national guidelines for laboratory testing was high, and screening identified two new HIV diagnoses.
The TelePrEP model achieved high adherence to guideline-indicated laboratory monitoring.
Two new HIV diagnoses were identified through the screening process.
The paper reports rapid linkage to treatment for clients with HIV identified on screening.
Methods
The nurse-led telehealth PrEP model was developed with a free multi-modal testing pathway at Sydney Sexual Health Centre (SSHC).
The model used a multi-modal testing pathway comprising at least three screening options: MyCheck, a[TEST], and Xpress.
The clinic was nurse-led and delivered via telehealth.
The service was designed to reduce burden on clinical services and provide convenience and access for clients.
Data were collected via retrospective review of electronic medical records.
Conclusions
The nurse-led TelePrEP model was concluded to be feasible in overcoming accessibility issues for key population groups including overseas-born men who have sex with men (MSM).
The model specifically addressed accessibility for overseas-born MSM, who comprised 86% of the client base.
The conclusion was supported by high overall attendance rates and high guideline adherence.
Rapid linkage to treatment for newly diagnosed HIV clients was also cited as evidence of feasibility.
What This Means
This study examined a new way of delivering HIV prevention medication (PrEP) through a nurse-led telehealth clinic called TelePrEP at Sydney Sexual Health Centre in Australia. Instead of requiring in-person visits to a doctor, clients could attend appointments by telehealth after completing STI and HIV testing through one of three free testing pathways. Researchers reviewed medical records from 472 clients to see how well the service worked, who used it, and whether clients came back for follow-up care.
The research suggests that the TelePrEP model successfully reached a population that can face significant barriers to healthcare access: the vast majority of clients were overseas-born (86%) and did not hold Australian Medicare (77%), meaning they would typically face out-of-pocket costs for medical care. The service achieved high attendance rates for initial appointments and strong adherence to recommended HIV and STI testing guidelines. Two new HIV diagnoses were made through the screening process, and those clients were quickly connected to treatment. However, only about a third of clients (36%) returned for recommended follow-up screening, with rates varying depending on which testing pathway they used.
This research suggests that nurse-led telehealth PrEP delivery, combined with free accessible testing options, can be an effective way to reach groups who might otherwise struggle to access HIV prevention services — particularly migrants and international visitors who may not have standard healthcare entitlements. The lower follow-up rates indicate that keeping clients engaged in ongoing care remains a challenge that future service models may need to address.
Wai J, Wong A, Ovington N, Robinson P, Varma R. (2025). Changing the model of HIV PrEP delivery - nurse-led telehealth in a metropolitan sexual health service: a retrospective analysis.. Sexual health. https://doi.org/10.1071/SH24081