Chinese visceral adiposity index as stronger predictor of hypertension and prehypertension in middle-aged and elderly Chinese adults: A comparative analysis with conventional adiposity indices.

CVAI showed a dose-response association with hypertension risk, with increasing odds ratios across quartiles compared to the lowest group.

• The ORs of risk of hypertension were 1.536, 2.088, and 3.391 for CVAI quartiles 2, 3, and 4 respectively, with the lowest quartile as reference.
• All comparisons were adjusted for selected covariates.
• Data were from Nanjing's 2017-2018 chronic disease surveillance for individuals over 45 years old.
• A generalized linear mixed model was used to assess the impact of CVAI and other indices.

LAP showed a significant but weaker association with hypertension risk compared to CVAI across quartiles.

• The ORs of risk of hypertension were 1.338, 1.845, and 2.489 for LAP quartiles 2, 3, and 4 respectively, with the lowest quartile as reference.
• These ORs were consistently lower than those observed for CVAI at equivalent quartile positions.
• Adjustments were made for selected covariates using a generalized linear mixed model.

TyG index was associated with hypertension risk but showed the weakest dose-response gradient among the continuous adiposity indices examined.

• The ORs of risk of hypertension were 1.277, 1.465, and 1.935 for TyG quartiles 2, 3, and 4 respectively, with the lowest quartile as reference.
• TyG showed lower ORs than CVAI, LAP, and BMI at all quartile levels.

BMI showed a strong dose-response association with hypertension risk, with the highest OR in the top quartile among all indices examined.

• The ORs of risk of hypertension were 1.396, 2.287, and 3.617 for BMI quartiles 2, 3, and 4 respectively, with the lowest quartile as reference.
• The top quartile OR for BMI (3.617) was numerically the highest among all adiposity indices for hypertension.
• Results were adjusted for selected covariates using a generalized linear mixed model.

Single-threshold adiposity indices (WC, WHtR, and WHR) showed more modest associations with hypertension compared to quartile-based indices.

• The OR for hypertension was 1.961 for waist circumference (WC), 1.915 for waist-to-height ratio (WHtR), and 1.299 for waist-to-hip ratio (WHR).
• These indices were analyzed as single threshold comparisons rather than quartile distributions.
• WHR showed the weakest association among all adiposity indices examined.

ROC analyses indicated CVAI was the strongest predictor of both hypertension and prehypertension compared to all other adiposity indices examined.

• ROC curve analysis was used to compare predictive accuracy across CVAI, LAP, TyG, BMI, WC, WHtR, and WHR.
• CVAI demonstrated superior predictive power for both hypertension and prehypertension outcomes.
• Similar associations were found for prehypertension as for hypertension across all adiposity variables.

Similar patterns of association were observed between all adiposity indices and prehypertension as were observed for hypertension.

• The study examined both hypertension and prehypertension as outcomes for all adiposity indices.
• Similar results were found in the impact of various obesity variables on prehypertension as on hypertension.
• CVAI was identified as the strongest predictor of prehypertension as well as hypertension in ROC analyses.

The study population consisted of middle-aged and elderly Chinese adults from Nanjing, analyzed using a generalized linear mixed model and ROC curves.

• Data were drawn from Nanjing's 2017-2018 chronic disease surveillance.
• The study included individuals over 45 years of age.
• A generalized linear mixed model was used to assess the impact of adiposity indices after adjusting for selected covariates.
• ROC curves were used to compare predictive accuracy of different adiposity indices.