Cardiovascular

Clinical impact of radial artery rupture during percutaneous transluminal angioplasty for radiocephalic arteriovenous fistula dysfunction: A single-center retrospective study.

TL;DR

Although radial artery rupture during percutaneous transluminal angioplasty for radiocephalic arteriovenous fistula dysfunction was relatively common (17.86%), it could be safely managed with prolonged low-pressure balloon inflation and localized compression, and did not appear to compromise long-term access-circuit patency.

Key Findings

Technical success was achieved in all 56 patients undergoing percutaneous transluminal angioplasty (PTA) for radial artery stenosis causing arteriovenous fistula dysfunction.

  • Single-center retrospective study conducted from January 2021 to September 2024.
  • All 56 patients who met inclusion criteria (AVF dysfunction with radial artery stenosis treated with arterial PTA) achieved technical success.
  • 100% technical success rate across the full cohort.

Radial artery rupture occurred in 10 of 56 patients (17.86%) during percutaneous transluminal angioplasty.

  • Rupture rate was 17.86% (10/56 patients).
  • All ruptures were successfully managed using prolonged low-pressure balloon inflation combined with localized external compression.
  • No covered stent implantation or surgical repair was required in any rupture case.
  • The authors described radial artery rupture as 'relatively common' in their cohort.

At 1 year, primary patency rates were not significantly different between the rupture group and the normal group.

  • Primary patency rate at 1 year was 40.0% in the rupture group (n=10) versus 39.1% in the normal group (n=46).
  • The difference was not statistically significant (p = 0.53).
  • These outcomes reflect overall access-circuit patency rather than lesion-level durability.

At 1 year, secondary patency rates were not significantly different between the rupture group and the normal group.

  • Secondary patency rate at 1 year was 90.0% in the rupture group versus 87.0% in the normal group.
  • The difference was not statistically significant (p = 0.35).
  • Authors noted these findings 'apply to overall access-circuit outcomes rather than lesion-level durability.'

Radial artery rupture during PTA did not appear to compromise long-term access-circuit patency in this cohort.

  • Both primary and secondary patency rates at 1 year were comparable between the rupture and non-rupture groups.
  • The authors concluded that 'controlled arterial rupture during percutaneous transluminal angioplasty appears to be a manageable procedural event that was not associated with worse overall access-circuit outcomes.'
  • Findings support conservative endovascular management (prolonged low-pressure balloon inflation plus localized compression) without routine stent or surgical intervention.

What This Means

This research examined what happens when the radial artery (the artery in the forearm) tears or ruptures during a balloon-based procedure used to open up narrowed blood vessels in patients who rely on a type of dialysis access called a radiocephalic arteriovenous fistula. These fistulas connect an artery and vein to allow for hemodialysis, and they frequently develop narrowings that need to be treated. The study followed 56 patients treated at a single center over about four years. It found that artery rupture happened in nearly 1 in 5 patients (about 18%) during the balloon procedure, which is a notable occurrence. Importantly, all ruptures were successfully treated by simply keeping the balloon inflated at low pressure for a longer period and applying gentle pressure from outside the skin — no surgical repair or metal stents were needed. The key practical finding is that patients whose arteries ruptured during the procedure did not have worse long-term outcomes compared to those whose arteries did not rupture. One year after treatment, about 40% of patients in both groups still had a functioning fistula without needing any additional procedures (primary patency), and about 87–90% still had a functioning fistula even after accounting for any additional interventions needed to keep it working (secondary patency). These differences were not statistically meaningful. This research suggests that artery rupture during balloon dilation for dialysis access problems, while alarming-sounding, can often be managed safely without escalating to more invasive treatments, and does not appear to harm the long-term function of the dialysis access. This has potential implications for how interventionists approach and counsel patients about this complication, though the study's single-center, retrospective design and relatively small sample size mean that larger, multi-center studies would be needed to confirm these findings.

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Citation

Yin J, Wei J, Fu L, Wang W, Wang F. (2026). Clinical impact of radial artery rupture during percutaneous transluminal angioplasty for radiocephalic arteriovenous fistula dysfunction: A single-center retrospective study.. The Journal of international medical research. https://doi.org/10.1177/03000605261480900