Cardiovascular

Clinical outcomes of arterial detection ligation technique for grade II/III versus grade IV hemorrhoidal disease.

TL;DR

ADL-mucopexy demonstrated comparable short-term clinical outcomes and patient satisfaction across different HD grades, suggesting it may be considered a potential minimally invasive surgical option in carefully selected patients with grade IV HD.

Key Findings

Patients with grade IV hemorrhoidal disease had significantly longer baseline toilet sitting times and symptom duration compared to grade II/III patients.

  • 78 total patients were included: grade II/III group n=54, grade IV group n=24
  • Patients were classified according to the Goligher classification
  • Study period was July 2022 to March 2024
  • These baseline differences were statistically significant between groups

Operative time and hospital stay were longer in the grade IV group compared to the grade II/III group.

  • 78 patients underwent ADL-mucopexy and were retrospectively analyzed
  • The number of mucopexies and external excisions performed was similar between the two groups
  • The ADL system provides deeper Doppler penetration and improved arterial mapping compared to standard Doppler-guided systems
  • These differences in operative time and hospital stay were noted despite similar procedural counts

Grade IV patients required more opioid analgesia and reported higher 24-hour visual analog scale pain scores postoperatively.

  • Grade IV patients experienced longer times to first flatus and defecation compared to grade II/III patients
  • 24-hour VAS pain scores were higher in the grade IV group
  • Tenesmus at 1 week was more common in grade IV patients
  • These differences reflected greater early postoperative discomfort in the grade IV group

One-month patient satisfaction scores were comparable between grade II/III and grade IV groups despite early postoperative differences.

  • Satisfaction scores at 1 month were 8.8 (grade II/III) versus 8.5 (grade IV)
  • Primary outcomes included postoperative pain and recurrence; secondary outcomes comprised operative time, tenesmus, bowel function parameters, and patient satisfaction
  • Despite greater early postoperative discomfort in grade IV patients, satisfaction scores converged by 1 month

Recurrence rates were low and similar between groups, with only one recurrence observed in each group during follow-up.

  • Recurrence was observed in 1 patient in the grade II/III group and 1 patient in the grade IV group
  • Recurrence was a primary outcome measure of the study
  • Doppler-guided dearterialization with mucopexy is described as well established for grade II/III HD, whereas evidence for grade IV disease was previously limited
  • The comparable recurrence rates support ADL-mucopexy as a viable option across HD grades

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Citation

Bilgiç &, Bölük S, Sobutay E, Bayraktar B. (2026). Clinical outcomes of arterial detection ligation technique for grade II/III versus grade IV hemorrhoidal disease.. Medicine. https://doi.org/10.1097/MD.0000000000048004