Clinical pearls addressing hair growth and loss in transgender patients on hormone replacement therapy.

Approximately 1.6% of US adults identify as transgender, representing a significant patient population with specific dermatological needs.

• The paper states 'about 1.6% of US adults identify as transgender'
• Within the transgender community, hair serves 'not only as a means of self-expression but also as a crucial element in affirming gender identity'
• Hair helps individuals 'align their outward appearance with their inner sense of self'

Significant disparities exist in care provided to transgender patients seeking masculine or feminine appearance through hormone replacement therapy.

• Studies on transgender patient satisfaction with current therapies are described as 'limited'
• Available studies 'indicate overall dissatisfaction with the standard of care'
• The paper identifies a gap in clinical guidance for dermatologists treating transgender patients

Dermatologists play a pivotal role in advocating and caring for transgender patients regarding their hair and skin needs.

• A deeper understanding of hormone replacement therapy and hair growth/loss therapy is described as 'crucial to prescribing medications aligned with patients' treatment goals'
• The commentary aims to provide clinical guidance to dermatologists in educating transgender patients undergoing hormone replacement therapy
• The paper addresses both transfeminine and transmasculine patient populations separately

Treatment algorithms for hair growth and loss were proposed specifically for transfeminine and transmasculine patients on hormone replacement therapy.

• Algorithms were based on multiple factors: 'efficacy, pharmacodynamic interactions with hormone replacement therapy, cost-effectiveness, adverse reactions, and care accessibility'
• Separate algorithms were tailored 'specifically for transfeminine and transmasculine patients'
• The algorithms were designed to address accessible options for both hair growth and hair loss