In this Whitehall II accelerometer substudy, clinical walking speed and free-living walking cadence were both associated with all-cause mortality and had similar discriminative ability, suggesting both measures can be used in population-based studies, with the choice depending on research objectives, implementation constraints, and each method's strengths.
Key Findings
Results
Higher clinical walking speed was associated with lower all-cause mortality risk in models adjusted for mortality risk factors.
HR was 0.77 (95% CI, 0.71-0.84) per 1 SD higher clinical walking speed.
Clinical walking speed was measured in meters per second from a 2.44-m walking test.
Models included sociodemographic, behavioral, and health-related factors.
The analysis included 4067 participants, with median (IQR) follow-up of 11.8 (11.5-12.1) years.
Results
Higher free-living walking cadence, measured by wrist-worn accelerometer, was associated with lower all-cause mortality risk.
Median walking cadence: HR, 0.83 (95% CI, 0.77-0.90) per 1 SD higher.
Cadence metrics (steps per minute) were derived from 9 days of wrist-worn accelerometer data.
Models were adjusted for sociodemographic, behavioral, and health-related mortality risk factors.
Results
Clinical walking speed and the two free-living cadence metrics had similar discriminative ability for all-cause mortality.
Clinical walking speed: C index, 0.747 (95% CI, 0.730-0.764).
Median walking cadence: C index, 0.744 (95% CI, 0.726-0.761).
95th percentile walking cadence: C index, 0.745 (95% CI, 0.727-0.762).
Discriminative ability was assessed using Harrell's concordance index in Cox models containing mortality risk factors.
Results
Only clinical walking speed was associated with improved discriminative ability when added to a model including mortality risk factors.
The cadence metrics did not improve discrimination of the model containing mortality risk factors.
This contrasts with the similar discriminative ability of the three measures in models that included them alongside risk factors.
Methods
The study sample was a population-based cohort of older adults with mortality follow-up of nearly 12 years.
4067 participants with valid accelerometer data, clinical walking speed, covariates, and electronic health records were included; mean (SD) age 69.3 (5.7) years; 3024 males (74.4%).
Baseline was January 2012 to December 2013, with follow-up through August 19, 2024.
All-cause mortality was ascertained from a British national mortality register.
Analyses used Cox proportional hazards regression.
What This Means
This study asked whether how fast people walk in a short clinic test predicts death as well as how fast they walk in everyday life, as measured by a wrist-worn activity tracker. It followed 4067 older adults in the UK (average age about 69) for around 12 years. Clinic walking speed came from a short 2.44-meter walk, while everyday walking pace (steps per minute) came from about 9 days of wearing an accelerometer.
Both kinds of measures were linked to lower risk of dying from any cause. People with faster clinic walking speeds or faster everyday walking cadence had a lower chance of death over follow-up, even after accounting for factors such as demographics, lifestyle, and health. The three measures (clinic speed, median cadence, and peak cadence) were similarly good at distinguishing who was more or less likely to die. However, only clinic walking speed added to the predictive ability of a model that already included standard risk factors.
This research suggests that both clinic-based and wearable-based walking measures can be useful in population studies, and the choice between them may depend on research goals and practical constraints. This is an observational study, so it shows associations rather than proving that walking faster causes longer life.
Check Your Own Numbers
Upload your bloodwork. We'll cross-reference your results against this study and 4,700 others.
Haddadj R, Danilevicz I, Rowlands A, van Hees V, Landré B, Le Faucheur A, et al.. (2026). Clinical Walking Speed, Free-Living Walking Cadence, and All-Cause Mortality.. JAMA network open. https://doi.org/10.1001/jamanetworkopen.2026.40122