Outcomes differed across ACM modalities and vendors, with a specific LTCM (iRhythm) associated with higher claims-based arrhythmia yield and lower repeat monitoring than most alternatives, and with lower hospitalization, health care utilization, and costs.
Key Findings
Results
Compared with iRhythm LTCM, Holter, MCT, and other LTCM had lower odds of arrhythmia diagnosis within 90 days.
IPTW-weighted ORs for arrhythmia diagnosis ranged from 0.50 to 0.95 for Holter, MCT, and other LTCM (p < 0.01)
AEM did not differ significantly from iRhythm LTCM in arrhythmia diagnosis odds
Arrhythmia diagnosis was assessed within 90 days of first ACM use
Among LTCM users, 58% received iRhythm LTCM, which served as the reference group
Results
Repeat monitoring within 180 days was higher for patients receiving other LTCM, AEM, and Holter compared with iRhythm LTCM.
IPTW-weighted ORs for repeat monitoring ranged from 1.99 to 2.77 for other LTCM, AEM, and Holter (p < 0.001)
MCT did not differ significantly from iRhythm LTCM in repeat monitoring rates
Repeat monitoring was assessed within 180 days of first ACM use
Results
All other ACM modalities had significantly higher odds of cardiovascular events within 365 days compared with iRhythm LTCM.
IPTW-weighted ORs for cardiovascular events ranged from 1.10 to 1.66 across all other modalities (p < 0.001)
Cardiovascular events were assessed over a 365-day follow-up period
Results
All other ACM modalities were associated with significantly higher odds of hospitalization within 365 days compared with iRhythm LTCM.
IPTW-weighted ORs for hospitalization ranged from 1.12 to 2.04 across all other modalities (p < 0.001)
Hospitalization was assessed over a 365-day follow-up period
Results
All other ACM modalities were associated with significantly higher odds of emergency department visits within 365 days compared with iRhythm LTCM.
IPTW-weighted ORs for ED visits ranged from 1.09 to 2.08 across all other modalities (p < 0.001)
ED visits were assessed over a 365-day follow-up period
Results
All other ACM modalities were associated with significantly higher healthcare costs within 365 days compared with iRhythm LTCM.
IPTW-weighted cost ratios ranged from 1.03 to 1.28 across all other modalities (p < 0.01)
Costs were assessed over a 365-day follow-up period
Methods
The study population comprised 352,782 patients receiving first ACM use between January 1, 2017 and June 30, 2022.
Mean age was 62.0 ± 17.1 years; 61% were female
25% received LTCM, 37% Holter, 20% AEM, and 18% MCT
Patients were commercially insured or Medicare Advantage beneficiaries without prior arrhythmia
Data were drawn from the Optum Research Database
Inverse probability of treatment weighting (IPTW) was used to adjust for confounding, with iRhythm LTCM as the reference
What This Means
This research examined how different types of wearable heart monitors perform in real-world clinical practice by analyzing insurance claims data from over 352,000 patients. The monitors studied included long-term continuous monitors (LTCM, such as patch monitors), traditional Holter monitors, ambulatory event monitors (AEM), and mobile cardiac telemetry (MCT). The study compared outcomes like whether an abnormal heart rhythm was detected, whether patients needed to repeat monitoring, and whether patients ended up in the hospital or emergency department within the following year.
This research suggests that the specific brand of monitor used matters, not just the monitor type. Patients who used a specific long-term continuous monitor (made by iRhythm Technologies) were more likely to receive an arrhythmia diagnosis within 90 days and less likely to need repeat monitoring compared to most other monitor types. Importantly, patients using other monitor types also had higher rates of hospitalization, emergency department visits, cardiovascular events, and overall healthcare costs over the following year compared to those using the iRhythm device.
The findings are based on a retrospective analysis of insurance claims rather than a randomized clinical trial, so other factors not fully captured in claims data could influence results. Nevertheless, the study confirms and extends similar findings previously observed in other patient populations, suggesting that the choice of ambulatory cardiac monitor may have meaningful downstream consequences for patient outcomes and healthcare resource use.
Mittal S, Reynolds M, Hughes A, Buysman E, Hendrickson E, Boyle K, et al.. (2026). Comparative Clinical Outcomes Across Ambulatory Cardiac Monitoring Modalities.. Clinical cardiology. https://doi.org/10.1002/clc.70500