Composite Phase Deviation (CPD) is a robust marker of circadian disruption in college students, with evening chronotype students showing greater misalignment and sleep irregularity than morning or intermediate types.
Key Findings
Results
Higher CPD was significantly associated with later rest onset as measured by actigraphy.
Association between CPD and sL5 (rest onset) was statistically significant at p < 0.001
sL5 refers to the onset of the least active 5-hour period, derived from actigraphy
Study used 14-day continuous wrist actigraphy in 46 college students (70% male)
Results
Higher CPD was significantly associated with lower interdaily stability (IS), indicating more irregular circadian rhythms.
Association between CPD and interdaily stability was significant at p = 0.0016
Interdaily stability measures day-to-day consistency of rest-activity patterns
Sample consisted of 46 college students wearing wrist actigraphs for two weeks
Results
Higher CPD was significantly associated with lower Sleep Regularity Index (SRI), indicating more irregular sleep patterns.
Association between CPD and SRI was statistically significant at p < 0.001
SRI quantifies the consistency of sleep-wake timing across days
Participants also completed PSQI, MCTQ, and MEQ questionnaires
Results
Later actigraphy-derived corrected mid-sleep time on free days (aMSFsc) was associated with worse subjective sleep quality.
Association between aMSFsc and PSQI score was significant at p = 0.047
aMSFsc was used as the actigraphy-derived chronotype measure
PSQI (Pittsburgh Sleep Quality Index) was used to assess subjective sleep quality
Results
Evening chronotype students exhibited higher CPD than both intermediate and morning chronotype students.
Chronotype was classified using aMSFsc, with morning types defined as earliest 25% and evening types as latest 25%
Group comparisons showed statistically significant differences in CPD between evening and other chronotype groups
The intermediate group fell between the morning and evening extremes
46 total participants were categorized into morning, intermediate, and evening groups
Results
Evening chronotype students had lower Sleep Regularity Index (SRI) compared to morning chronotype students.
Group comparison of SRI showed significant difference between evening and morning types
No significant difference in SRI was reported between evening and intermediate types in group comparisons
This finding reinforces that evening chronotypes experience more irregular sleep patterns
Results
No significant group differences in Light Regularity Index (LRI) were observed across chronotype groups.
LRI measures the regularity of light exposure patterns across days
Despite no group-level differences, CPD was negatively associated with LRI at lower light thresholds
This suggests that the relationship between light regularity and circadian disruption may be threshold-dependent
Results
CPD was negatively associated with Light Regularity Index (LRI) at lower light thresholds.
The negative association indicates that lower light regularity corresponds to higher CPD (more circadian disruption)
This association was specific to lower light intensity thresholds
No overall group differences in LRI were found despite this individual-level association
What This Means
This research suggests that a measure called Composite Phase Deviation (CPD), calculated from two weeks of wrist-worn activity monitors, can reliably identify disruption in the body's internal clock among college students. Students who had higher CPD scores tended to go to sleep later, had less consistent daily activity patterns, and slept at more irregular times. Students with an 'evening' preference—those who naturally stay up late and wake up late—showed the most circadian disruption and the most irregular sleep schedules compared to 'morning' types.
The study also found that students with later natural sleep timing reported worse sleep quality on a standard questionnaire, and that irregular patterns of light exposure were linked to more circadian disruption, particularly at lower light intensity levels. However, there were no significant differences in overall light regularity between chronotype groups, suggesting light exposure patterns may influence circadian disruption in more subtle ways.
This research suggests that college students with evening chronotypes are especially vulnerable to circadian misalignment, likely because academic schedules are structured around early morning hours that conflict with their biological clocks. The findings point to a need for both individual-level sleep health interventions and broader structural changes in academic environments—such as later class start times—to better accommodate students whose internal clocks naturally run later.
Guimarães Nogueira M, Umemura G, Vallim J, da Costa Lopes L, D Almeida V, Forner-Cordero A. (2026). Composite Phase Deviation as a marker of circadian disruption in college students: Associations with chronotype, sleep, and light regularity.. Chronobiology international. https://doi.org/10.1080/07420528.2025.2606255