Exercise & Training

Configurational patterns associated with relatively higher recent home-based exercise behavior among lung transplant recipients: a fuzzy-set qualitative comparative analysis.

TL;DR

Relatively higher recent home-based exercise behavior among lung transplant recipients within the first year after transplantation was associated with multiple configurations of capability-, social opportunity-, and motivation-related conditions rather than any single necessary condition.

Key Findings

No single COM-B-related condition was necessary for relatively higher recent home-based exercise behavior among lung transplant recipients.

  • The study included 139 adult lung transplant recipients within the first year after transplantation at a tertiary hospital in Zhejiang, China.
  • Five conditions were tested: 6-min walk distance, exercise rehabilitation knowledge, perceived social support, exercise self-efficacy, and exercise automaticity.
  • Fuzzy-set qualitative comparative analysis (fsQCA) necessary-condition analysis found no single condition necessary for the outcome.

Four sufficient configurations were identified that together explained relatively higher recent home-based exercise behavior.

  • Overall solution coverage was 0.675.
  • Overall solution consistency was 0.827.
  • The configurations were summarized as motivation-characterized and multi-condition synergistic patterns.

Motivation-characterized configurations combined higher exercise self-efficacy with higher exercise automaticity.

  • One of these configurations involved relatively limited exercise capacity.
  • That configuration was sensitive to the calibration scheme (calibration-sensitive).

Multi-condition synergistic configurations involved favorable combinations of capability-, social opportunity-, and motivation-related conditions.

  • One configuration was characterized by rehabilitation knowledge, social support, and exercise automaticity.
  • Another was characterized by better exercise capacity, higher rehabilitation knowledge, exercise self-efficacy, and some social support.

Analysis of the negated outcome supported causal asymmetry.

  • fsQCA examined the negated outcome (relatively lower recent home-based exercise behavior) in addition to the presence of the outcome.
  • The results supported causal asymmetry, meaning conditions leading to higher exercise do not simply mirror those leading to lower exercise.

Exploratory univariate analyses highlighted postoperative stage and pulmonary function as clinical context related to exercise behavior.

  • These analyses were described as exploratory and used to describe clinical context.
  • Recent exercise behavior was measured over the previous 7 days via structured retrospective interviews and calculated as MET-min/week.

The study used the COM-B model as its framework and a cross-sectional design to examine configurations associated with exercise behavior.

  • Conditions mapped to capability, opportunity (social), and motivation components of COM-B.
  • The authors suggest findings may inform multidimensional assessment and clinically contextualized rehabilitation support during post-transplant home recovery.

What This Means

This study looked at what factors go together with higher levels of home-based exercise in people in the first year after a lung transplant. Researchers surveyed and interviewed 139 recipients at a hospital in China, measuring walking ability, knowledge about exercise rehabilitation, perceived social support, confidence in exercising, and how automatic exercise felt. They then used a method that looks at combinations of factors rather than each factor alone. No single factor was required for a person to have relatively higher recent exercise. Instead, four different combinations were linked to higher exercise. Two combinations centered on motivation, pairing high exercise confidence with exercise being a habit. Others involved a mix of knowledge, social support, habit, better walking capacity, and confidence. One motivation-based pattern involving limited exercise capacity changed depending on how the data were categorized, so it is less certain. The factors linked to lower exercise were not simply the opposite of those linked to higher exercise, and time since surgery and lung function also appeared relevant. This research suggests that supporting exercise at home after lung transplant may work best when several aspects, such as knowledge, social support, confidence, and habit, are assessed together and tailored to the individual's clinical situation. Because the study was cross-sectional, in one hospital, and relied on recalled exercise over 7 days, it cannot show that any combination causes more exercise.

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Citation

Zhu Q, Tang L, Lin P, Zeng F, Lan M. (2026). Configurational patterns associated with relatively higher recent home-based exercise behavior among lung transplant recipients: a fuzzy-set qualitative comparative analysis.. Annals of medicine. https://doi.org/10.1080/07853890.2026.2756039