Sleep

[Differential study on sleep architecture and sleep subtypes in children with OSA in different weight states].

TL;DR

The prevalence of P-OSA was higher among overweight and obese groups, with the obese group experiencing the highest rates of severe OSA, more frequent hypoxemia, and reduced REM sleep duration.

Key Findings

Obese children with OSA had significantly elevated respiratory indices compared to all other weight groups.

  • Group D (obese) had significantly higher OAHI, AHI, ODI, HI, and NREMAHI than Groups A, B, and C (P<0.05).
  • REMAHI was lower in Groups A (normal weight) and C (overweight) compared to Group D (obese) (P<0.05).
  • The study used polysomnographic monitoring data collected retrospectively from January 1, 2017 to December 30, 2022.

Obese children with OSA had lower oxygen saturation levels during both NREM and REM sleep compared to normal weight children.

  • Minimum oxygen saturation, minimum oxygen saturation during NREM sleep, and minimum oxygen saturation during REM sleep were all lower in Group D (obese) than in Group A (normal weight) (P<0.05).
  • This pattern indicates more frequent hypoxemia in the obese group.
  • The comparison was specifically significant between Group D and Group A only, as reported in the abstract.

The proportion of children with severe OSA was highest in the obese group.

  • The proportion of children with severe OSA was higher in Group D (obese) than in all other groups (Groups A, B, and C) (P<0.05).
  • Adenoid size distribution showed no significant difference among the four weight groups.
  • Children were categorized as normal weight (Group A), underweight (Group B), overweight (Group C), and obese (Group D).

Normal weight and underweight children with OSA had higher percentages of REM sleep than obese children.

  • Groups A (normal weight) and B (underweight) exhibited higher percentages of REM sleep than Group D (obese) (P<0.05).
  • This finding indicates that obesity is associated with reduced REM sleep duration in children with OSA.
  • REM sleep percentage was compared across all four weight groups using polysomnographic data.

The incidence of positional OSA (P-OSA) was significantly higher in overweight and obese children compared to normal weight and underweight children.

  • The incidence of P-OSA in Group C (overweight) was higher than in Groups A (normal weight) and B (underweight) (P<0.05).
  • The incidence of P-OSA in Group D (obese) was also higher than in Groups A and B (P<0.05).
  • P-OSA refers to positional obstructive sleep apnea, a subtype where sleep position significantly influences apnea events.

The incidence of REM-related OSA (R-OSA) did not differ significantly among the four weight groups.

  • No significant difference was found in the incidence of R-OSA among Groups A, B, C, and D.
  • R-OSA refers to REM-related obstructive sleep apnea, a subtype where apnea events are concentrated during REM sleep.
  • This contrasts with P-OSA, which showed significant differences by weight category.

Significant gender differences were observed between certain weight groups.

  • Statistically significant gender differences were found between Groups A and D (normal weight vs. obese), B and C (underweight vs. overweight), and B and D (underweight vs. obese).
  • No significant gender difference was noted between all pairs of groups.
  • This finding suggests that gender distribution was not uniform across weight categories in the study sample.

What This Means

This research suggests that body weight plays an important role in how obstructive sleep apnea (OSA) — a condition where breathing repeatedly stops during sleep — affects children's sleep patterns and severity. By analyzing sleep study records from children seen between 2017 and 2022 and grouping them by weight (underweight, normal weight, overweight, and obese), researchers found that obese children had the most severe forms of OSA, the most breathing disruptions, the lowest blood oxygen levels during sleep, and the least amount of REM (dream-stage) sleep compared to children of normal weight. The study also identified differences in OSA subtypes by weight. Positional OSA — where symptoms are strongly tied to sleeping position — was more common in both overweight and obese children than in normal or underweight children. In contrast, REM-related OSA (where breathing problems occur mainly during dream sleep) did not differ significantly by weight group. Interestingly, adenoid size, which is often a key factor in childhood OSA, did not differ meaningfully across weight groups, suggesting that weight-related factors may operate through different mechanisms. This research suggests that clinicians should consider a child's weight status when diagnosing and managing OSA, as obese children may need more intensive monitoring and treatment given their higher risk of severe disease and dangerous drops in blood oxygen. The higher rate of positional OSA in overweight and obese children also opens the possibility of position-based therapies as part of a personalized treatment approach for these patients.

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Citation

Luo C, Li Q. (2026). [Differential study on sleep architecture and sleep subtypes in children with OSA in different weight states].. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery. https://doi.org/10.13201/j.issn.2096-7993.2026.03.012