Dietary Supplements

Disolución exitosa de un bezoar gigante tras tratamiento con complejo enzimático.

TL;DR

A conservative approach using an oral enzyme complex (Digeston Plus®) containing digestive enzymes and probiotic bacteria led to symptom resolution and near-complete dissolution of a giant gastric phytobezoar without invasive intervention after a three-month treatment course.

Key Findings

A giant gastric phytobezoar in a 67-year-old man was successfully treated with an oral enzyme complex over three months.

  • The patient was a 67-year-old man with a previously asymptomatic giant gastric phytobezoar who developed subocclusive symptoms.
  • Treatment consisted of an oral enzyme complex (Digeston Plus®) containing digestive enzymes and probiotic bacteria.
  • The patient completed a three-month treatment course.
  • Outcomes included symptom resolution and near-complete dissolution of the bezoar without the need for invasive intervention.

Bezoars are an uncommon cause of intestinal obstruction and no standard therapy currently exists for giant bezoars.

  • A review of the literature was performed to evaluate available treatment strategies.
  • The authors note that no standard therapy exists to date for giant bezoars.
  • Multiple management approaches exist, including invasive and surgical treatments.
  • The authors suggest invasive or surgical treatments should not be considered first-line when conservative options are feasible, as recurrence can occur.

Conservative management with an enzyme complex was selected as the treatment approach for this giant phytobezoar case.

  • The enzyme complex Digeston Plus® was used, containing digestive enzymes and probiotic bacteria.
  • The conservative approach was chosen over invasive intervention given the feasibility of non-invasive options.
  • The treatment duration was three months.
  • This case represents a report of successful non-invasive dissolution of a giant bezoar using this specific enzyme complex formulation.

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Citation

Sabatella L, Gascón Jiménez J, Blanco N, Rotellar F, Valentí V. (2026). Disolución exitosa de un bezoar gigante tras tratamiento con complejo enzimático.. Anales del sistema sanitario de Navarra. https://doi.org/10.23938/ASSN.1154