Most dobutamine stress echocardiograms performed at our institution were conducted in asymptomatic patients, although recent European guidelines no longer support this systematic screening approach, suggesting a need to optimise patient selection and adopt multiparametric protocols.
Key Findings
Results
The study population was predominantly male with a high cardiovascular risk factor burden.
71% of patients were male
Mean age was 71.2 years
41.4% of patients had three or more cardiovascular risk factors
Total sample: 111 consecutive patients examined at Sainte-Anne Military Hospital during the 2023-2024 academic year
Results
The most common indication for dobutamine stress echocardiography was routine follow-up of known coronary artery disease.
45.9% of examinations were performed as part of routine follow-up of known coronary artery disease
14.4% were performed for investigation of angina
Most examinations were performed in asymptomatic patients
Recent European guidelines no longer support this systematic screening approach in asymptomatic patients
Results
A notable proportion of patients had already undergone coronary assessment within the preceding 24 months prior to the dobutamine stress echocardiogram.
21 patients (18.9%) had already undergone coronary assessment within the preceding 24 months
This finding raises concerns regarding appropriateness of indications and cost-effectiveness
Since 2017, the cost of the examination in France has increased following its integration into the diagnosis-related group reimbursement system
Results
Image quality was acceptable at rest in most cases but declined at peak stress, and contrast agents were rarely used.
Image quality was acceptable or better in 90% of cases at rest
Image quality was acceptable or better in 79% of cases at peak stress
Contrast agents were used in only two patients
Broader adoption of multiparametric protocols could improve diagnostic yield and safety
Results
Wall motion abnormalities were detected in a small proportion of cases, and roughly half of patients who underwent subsequent coronary angiography were revascularised.
Wall motion abnormalities were detected in only 2.7% of cases
16 patients underwent coronary angiography following the examination
Of those 16 patients, 8 (50%) were revascularised
The low rate of wall motion abnormalities suggests a potentially low diagnostic yield in this predominantly asymptomatic population
What This Means
This research examined how appropriately dobutamine stress echocardiography (a cardiac stress test using medication to simulate exercise while imaging the heart with ultrasound) was being used at a single French military hospital over one academic year. The study looked at 111 patients who underwent the test and evaluated whether the reasons for ordering the test matched current medical guidelines, and whether the test was being performed according to recommended protocols.
The study found that the most common reason for ordering the test was routine monitoring of patients already known to have coronary artery disease, and that most tests were performed in patients who had no symptoms. However, current European guidelines no longer recommend this kind of routine, systematic screening in asymptomatic patients. Additionally, nearly one in five patients had already had a coronary evaluation within the previous two years, raising questions about whether repeated testing was necessary. The test detected meaningful abnormalities (wall motion problems) in only about 1 in 37 patients, and image quality at peak stress was suboptimal in about 1 in 5 cases, partly because a contrast agent to improve image quality was almost never used.
This research suggests that there is room to improve how this test is used: better patient selection focusing on symptomatic individuals, and more consistent use of recommended techniques such as contrast agents and multiparametric protocols, could make the test more effective, safer, and more cost-efficient. This is particularly relevant in France, where the reimbursement structure for the test changed in 2017, making appropriate use increasingly important from a healthcare cost perspective.
Demoulin R, Prevautel T, Schmitt P, Adet A, Capilla E, Rohel G, et al.. (2026). [Dobutamine stress echocardiography: Appropriateness of indications and protocol compliance. A single-centre report].. Annales de cardiologie et d'angeiologie. https://doi.org/10.1016/j.ancard.2026.102016