A hybrid approach combining double-barrel STA-MCA bypass with endovascular parent artery occlusion offers a safe and effective treatment option for complex intracranial aneurysms, providing reliable flow restoration and durable aneurysm exclusion.
Key Findings
Results
All patients achieved confirmed aneurysm exclusion and preserved perfusion following the double-barrel STA-MCA bypass with endovascular parent artery occlusion.
Seven patients were included in the analysis with a mean age of 44.7 ± 27.5 years; 57.1% were male.
Postoperative DSA confirmed aneurysm exclusion and preserved perfusion in all 7 cases.
At long-term follow-up, all aneurysms remained completely occluded and bypass patency was maintained in all patients.
Follow-up was conducted at 1-, 3-, and 6-month post-procedure and annually thereafter, including clinical assessment and imaging with MRI/MRA or DSA.
Results
No permanent neurological deficits or bypass failures were observed in the study cohort.
One patient developed transient hemiparesis, which resolved spontaneously without intervention.
One emergency case involved a double-barrel bypass performed following coil prolapse and occlusion of both M2 segments during endovascular embolization; this patient was discharged with mild residual contralateral paresis.
No permanent neurological deficits were recorded across all 7 patients.
No bypass failures were observed at any follow-up time point.
Results
The majority of aneurysms treated were fusiform and located in the middle cerebral artery.
85.7% of aneurysms were fusiform in morphology.
71.4% of aneurysms were located in the MCA.
The study focused on giant or fusiform intracranial aneurysms treated between January 2019 and January 2025.
All 7 patients underwent both double-barrel bypass and endovascular occlusion of the parent artery.
Results
The hybrid approach was feasible in an emergency setting following iatrogenic endovascular complication.
One patient required emergency double-barrel bypass after coil prolapse caused occlusion of both M2 segments during endovascular embolization.
The patient in the emergency case was discharged with only mild residual contralateral paresis.
This case demonstrated the utility of performing the procedure in a hybrid operating setting.
Conclusions
The hybrid operating setting was identified as a key factor in enabling the combined surgical and endovascular approach for complex intracranial aneurysms.
The procedure involved double-barrel STA-MCA bypass followed by endovascular occlusion of the parent artery.
The authors concluded this strategy is particularly effective 'when performed in a hybrid operating setting.'
The study period spanned January 2019 to January 2025, representing a retrospective observational design.
Nurimanov C, Menlibayeva K, Mammadinova I, Kaliyev A, Makhambetov Y, Akshulakov S. (2026). Double-barrel STA-MCA bypass with endovascular parent artery occlusion for complex anterior circulation aneurysms: indications and outcomes.. Acta neurochirurgica. https://doi.org/10.1007/s00701-026-06833-3