Poor sleep quality (PSQI score >9.5) emerged as the only variable significantly associated with fall history in older adults with T2DM, suggesting that fall risk in this population 'is a multidimensional construct' influenced more by behavioral and psychological factors than isolated motor metrics.
Key Findings
Results
TUG and TUG-DT times were significantly longer in adults with T2DM compared to healthy controls.
TUG time difference was statistically significant (p = 0.034)
TUG-DT time difference was highly significant (p < 0.001)
Study involved 30 patients with T2DM and 30 age- and gender-matched healthy controls, all aged over 50
The T2DM group showed greater impairment on the dual-task version than on the single-task TUG
Results
TUG-DT performance was significantly more impaired in the T2DM group, with increased cognitive errors, cognitive pauses, and movement pauses.
Cognitive errors were significantly higher in the T2DM group (p = 0.015)
Cognitive pauses were significantly more frequent in the T2DM group (p < 0.001)
Movement pauses were also significantly more frequent in the T2DM group (p = 0.021)
These findings indicate that the TUG-DT test is sensitive to detecting declines in functional mobility associated with T2DM
Results
Postural stability and visual preference differed significantly between the T2DM group and healthy controls.
Postural stability was significantly different between groups (p < 0.05)
Visual preference was significantly different between groups (p = 0.045)
Balance was assessed via postural stability measures as part of a multi-domain assessment
Results
Depression scores and lifestyle factors including smoking and exercise behavior differed significantly between the T2DM and control groups.
CES-D (Center for Epidemiologic Studies Depression Scale) scores were significantly different between groups (p = 0.015)
Smoking behavior differed significantly between groups (p = 0.01)
Exercise behavior differed significantly between groups (p < 0.001)
Alcohol and tea intake were also assessed but were not reported as statistically significant between groups
Results
Within the T2DM group, PSQI (Pittsburgh Sleep Quality Index) score was the only variable significantly associated with fall history in logistic regression analysis.
PSQI was the only significant predictor of fall status among T2DM participants (OR = 1.239, 95% CI: 1.033–1.488)
The T2DM cohort was stratified into faller and non-faller subgroups for this analysis
Variables assessed in the regression included TUG, TUG-DT, postural stability, FES-I, CES-D, PSQI, and lifestyle factors
Motor metrics such as TUG and TUG-DT time did not independently predict fall history within the T2DM group
Results
ROC analysis showed that PSQI had acceptable discriminative ability for identifying fallers among adults with T2DM, with an optimal cut-off score of 9.5.
Optimal cut-off value of 9.5 yielded a sensitivity of 72.7% and a specificity of 84.2%
A PSQI score greater than 9.5 was identified as a critical correlate of falls in this population
Conclusions
The study concluded that fall risk in individuals with T2DM is a multidimensional construct primarily influenced by behavioral and psychological factors rather than isolated motor metrics.
Despite TUG-DT being sensitive to detecting functional mobility declines in T2DM, it did not independently predict fall history
Poor sleep quality emerged as the primary modifiable correlate of fall history within the T2DM group
Fear of falling was assessed via the Falls Efficacy Scale International (FES-I) but was not identified as a significant independent predictor in regression
Cross-sectional design limits causal inference; findings indicate association, not causation
What This Means
This study examined what factors are associated with a history of falls in older adults with type 2 diabetes (T2DM), comparing 30 people with T2DM to 30 healthy adults of similar age and gender. Researchers looked at walking and balance performance, sleep quality, depression, fear of falling, and lifestyle habits like smoking and exercise. They found that people with T2DM walked more slowly, made more mental errors, and paused more often during a walking-while-thinking test (called the Dual-Task Timed Up and Go, or TUG-DT) compared to healthy controls. They also showed poorer balance, higher depression scores, smoked more, and exercised less.
When the researchers looked specifically at which T2DM patients had a history of falling versus those who had not, poor sleep quality—measured by a standard questionnaire called the Pittsburgh Sleep Quality Index (PSQI)—was the only factor that statistically predicted fall history. A PSQI score above 9.5 identified past fallers with 72.7% sensitivity and 84.2% specificity. Notably, the walking and balance tests, despite showing clear differences between the T2DM and healthy groups, did not independently predict who had fallen within the T2DM group.
This research suggests that fall prevention programs for older adults with type 2 diabetes should look beyond physical fitness and mobility assessments alone. Screening for poor sleep quality may be a practical and important step in identifying individuals at higher fall risk. Because this was a cross-sectional study (a snapshot in time with a relatively small sample of 60 participants), it cannot prove that poor sleep causes falls, but it highlights sleep as a potentially important and modifiable target for further investigation and intervention.
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Zhang X, Wang S, Sun C, Li S, Hu Y. (2026). Dual-task timed up and go performance and sleep quality in relation to fall history in older adults with type 2 diabetes: a cross-sectional study.. Frontiers in public health. https://doi.org/10.3389/fpubh.2026.1856870