Eating Disorders in People Who Identify as Gender-Diverse: Associations Between Gender Diversity, Eating Disorder Diagnosis, Minority Stress Experiences and Mental Health Comorbidity.
GD individuals with an ED had significantly more comorbid MH diagnoses than non-GD individuals with an ED and GD individuals without an ED, and ED diagnosis in GD individuals was associated with increased odds of experiencing minority stress events and associated distress.
Key Findings
Results
Gender-diverse individuals with an eating disorder had significantly more comorbid mental health diagnoses than non-gender-diverse individuals with an eating disorder.
GD participants with an ED had a mean of 4.23 (SD = 2.23) comorbid MH diagnoses compared to 2.86 (SD = 1.98) in non-GD individuals with an ED.
Comparison groups were demographically matched from a sample of 334,957 American university and college students.
The GD with ED group consisted of 1885 individuals.
The difference was described as statistically significant even following 'stringent demographic matching.'
Results
Gender-diverse individuals with an eating disorder had significantly higher mental health comorbidity than gender-diverse individuals without an eating disorder.
GD participants with an ED had a mean of 4.23 (SD = 2.23) comorbid MH diagnoses compared to 1.96 (SD = 1.84) in GD individuals without an ED.
Comparisons were made using demographically matched samples.
The elevated comorbidity included serious mental health disorders.
The sample was drawn from a large cross-sectional survey of American university and college students.
Results
Eating disorder diagnosis in gender-diverse individuals was associated with increased odds of experiencing minority stress events.
ED diagnosis was associated with increased odds of experiencing minority stress events (OR: 2.19, 95% CI [1.91–2.51]).
ED diagnosis was also associated with increased odds of distress related to minority stress events (OR: 2.17, 95% CI [1.89–2.50]).
These associations were identified within the gender-diverse subsample.
The analysis used Gender Minority Stress Theory as a theoretical framework to explain elevated ED risk in GD populations.
Methods
The study used a large cross-sectional survey dataset of American university and college students to compare mental health outcomes across gender and eating disorder status.
Total sample size was 334,957 American university and college students.
1885 gender-diverse individuals with an eating disorder were identified.
Demographically matched comparison groups were created for non-GD individuals with an ED and GD individuals without an ED.
The study design was cross-sectional, based on survey data.
Background
Mental health comorbidity is elevated both in gender-diverse individuals and in individuals with eating disorders, and those with both conditions may face compounded risk.
The background of the study notes that MH comorbidity is elevated in GD individuals and in individuals with an ED independently.
GD individuals with an ED were hypothesized to have significantly higher MH comorbidity than those with only one of these conditions.
Gender Minority Stress Theory is cited as a potential explanatory framework for elevated ED risk in GD populations.
The authors identified the need for prompt intervention and proactive screening in this population.
Murphy R, Sharpe H. (2026). Eating Disorders in People Who Identify as Gender-Diverse: Associations Between Gender Diversity, Eating Disorder Diagnosis, Minority Stress Experiences and Mental Health Comorbidity.. Nutrients. https://doi.org/10.3390/nu18030458