Cardiovascular

Effect of modified air-pulse stimulation on tracheotomised patients with dysphagia after stroke: A randomized clinical trial.

TL;DR

Modified air-pulse stimulation delivered via flexible endoscopy is an effective therapy for improving swallowing function in tracheotomized stroke patients with dysphagia, producing significantly better outcomes than conventional air-pulse stimulation across all measured indicators.

Key Findings

Modified flexible endoscopy-mediated air-pulse stimulation significantly improved Murray Secretion Scale scores compared to conventional air-pulse stimulation.

  • 47 subacute stroke patients with tracheotomy and dysphagia were randomized into control and trial groups
  • Both groups received personalized swallowing rehabilitation training in addition to their respective stimulation interventions
  • The trial group showed significantly better Murray Secretion Scale scores than the control group (P < .01)
  • No statistical difference existed between the two groups at baseline (P > .5)

The trial group demonstrated significantly better Penetration-Aspiration Scale scores than the control group.

  • Penetration-Aspiration Scale was used to assess swallowing function in both groups
  • The trial group performed significantly better than the control group on the Penetration-Aspiration Scale (P < .01)
  • This outcome was assessed in 47 subacute stroke patients requiring tracheotomy

Spontaneous swallowing frequency was significantly higher in the trial group receiving modified air-pulse stimulation compared to the control group.

  • Spontaneous swallowing frequency was one of the primary swallowing function outcome indicators
  • The trial group performed significantly better than the control group in spontaneous swallowing frequency (P < .01)
  • Both groups received personalized swallowing rehabilitation training as a common intervention

Modified air-pulse stimulation significantly reduced pneumonia severity as measured by the Clinical Pulmonary Infection Score compared to conventional stimulation.

  • Clinical Pulmonary Infection Score was used to assess pneumonia severity in both groups
  • The trial group performed significantly better than the control group on Clinical Pulmonary Infection Score (P < .01)
  • Post-stroke dysphagia with tracheotomy imposes significant physical and financial burdens on patients, making pulmonary infection a key clinical concern

Nutritional status indicators were significantly improved in the trial group compared to the control group.

  • Hemoglobin and serum prealbumin levels were used to evaluate nutritional status
  • The trial group showed significantly better hemoglobin levels than the control group (P < .05)
  • Prealbumin levels were significantly better in the trial group compared to the control group (P < .0001)
  • Prealbumin showed the most statistically significant between-group difference of all outcome measures

The study population consisted of subacute stroke patients with both tracheotomy and dysphagia, a population for which targeted interventions remain limited.

  • 47 subacute stroke patients with tracheotomy and dysphagia were enrolled
  • Post-stroke dysphagia is described as highly prevalent, particularly among severe cases requiring tracheotomy
  • Currently, targeted interventions specifically designed to improve swallowing function in this tracheotomised stroke population remain limited
  • Patients were randomized into control and trial groups with no statistical difference at baseline (P > .5)

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Citation

Gao Y, Pan W, Cao J, Jiang Y, Du Y. (2026). Effect of modified air-pulse stimulation on tracheotomised patients with dysphagia after stroke: A randomized clinical trial.. Medicine. https://doi.org/10.1097/MD.0000000000048075