Sleep

Effect of Sleep on Cardiorespiratory Fitness of Apparently Healthy Young Adults.

TL;DR

Significant impact of sleep quality on cardiorespiratory fitness assessed by VO2 max could not be established in apparently healthy young adults.

Key Findings

There was no significant difference in VO2 max between participants with normal sleep and those with poor sleep quality.

  • Mean VO2 max in normal sleep category was 42.50 ± 8.61 mL/kg/min
  • Mean VO2 max in poor sleep category was 41.89 ± 7.97 mL/kg/min
  • Independent samples t-test yielded p=0.77, indicating no statistically significant difference
  • Participants were categorized using Pittsburgh Sleep Quality Index (PSQI) scores

No correlation was found between PSQI score and VO2 max in young medical students.

  • Pearson's correlation coefficient r=0.029
  • Correlation was not statistically significant (p=0.591)
  • VO2 max was calculated using post-exercise heart rate from the Queen's College Step Test
  • Total sample size was 64 participants

The study sample consisted of 64 apparently healthy young medical students with similar mean PSQI scores across sexes.

  • 45 participants were male and 19 were female
  • Mean PSQI score in male participants was 5.53 ± 2.76
  • Mean PSQI score in female participants was 5.52 ± 3.44
  • Study was conducted from March 2023 to September 2024 at Maharajgunj Medical Campus, Nepal
  • Study design was cross-sectional and analytical

Cardiorespiratory fitness was assessed using the Queen's College Step Test with post-exercise heart rate monitoring to calculate VO2 max.

  • Heart rate was monitored post-exercise to calculate VO2 max
  • Participants from both normal and poor sleep categories performed the same step test protocol
  • This is a non-invasive, submaximal exercise test commonly used in field settings

What This Means

This research suggests that sleep quality, as measured by the Pittsburgh Sleep Quality Index (PSQI), does not significantly affect cardiorespiratory fitness in apparently healthy young adults. The study measured aerobic fitness (VO2 max — the maximum amount of oxygen the body can use during exercise) in 64 young medical students in Nepal, comparing those who reported normal sleep to those who reported poor sleep. Despite dividing participants into these two groups, the researchers found nearly identical VO2 max values between them, and no meaningful statistical relationship between sleep quality scores and fitness levels. The study used a step-test exercise protocol — a simple, practical method for estimating fitness — and assessed sleep using a validated questionnaire. Both male and female participants had very similar average sleep quality scores, suggesting the sample as a whole experienced a moderate level of sleep disruption, which is common among medical students. The absence of a relationship between sleep quality and fitness in this group may reflect the resilience of young, otherwise healthy individuals, or the limited sensitivity of the measures used. This research suggests that among apparently healthy young adults, short-term or moderate sleep disturbances may not translate into measurable declines in cardiorespiratory fitness. However, the cross-sectional design means the study cannot track changes over time, and the relatively small and homogeneous sample (medical students) may limit how broadly these findings apply. Longer-term studies with more diverse populations would be needed to fully understand how chronic sleep problems might affect physical fitness.

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Citation

Kandel S, Mahotra N, Shrestha L, Bajimaya M, Aryal V. (2026). Effect of Sleep on Cardiorespiratory Fitness of Apparently Healthy Young Adults.. Journal of Nepal Health Research Council. https://doi.org/10.33314/jnhrc.v24i01.4730