Dietary Supplements

Effects of Dietary Nitrate and Caffeine on End Power and Work Above End Power During a 3 min All-Out Test in Trained Male Cyclists.

TL;DR

No statistically significant differences between conditions were detected under the conditions of the present study for end power, work above end power, peak power, mean power, or total work during a 3 min all-out test.

Key Findings

Dietary nitrate supplementation via beetroot juice had no significant effect on end power during a 3-minute all-out cycling test.

  • End power was not significantly different across conditions (p = 0.401, ηp2 = 0.056)
  • Participants consumed approximately 13 mmol NO3- in nitrate-rich beetroot juice three hours before exercise
  • The nitrate-depleted placebo beverage served as the control for the beetroot juice condition
  • 15 trained male cyclists completed all four conditions in a randomized, double-blind, placebo-controlled, crossover design

Caffeine supplementation had no significant effect on end power during a 3-minute all-out cycling test.

  • End power was not significantly different across conditions (p = 0.401, ηp2 = 0.056)
  • Caffeine was administered at 5 mg·kg-1 body mass one hour before testing
  • Maltodextrin placebo capsules served as the control for the caffeine condition
  • Effect size for end power was small (ηp2 = 0.056)

Neither dietary nitrate nor caffeine, alone or in combination, significantly affected work performed above end power during the 3-minute all-out test.

  • Work above end power (WEP) was not significantly different across conditions (p = 0.580, ηp2 = 0.048)
  • The four conditions tested were: placebo + placebo, beetroot juice + placebo (BR), placebo + caffeine (CAF), and beetroot juice + caffeine (BR + CAF)
  • Effect size for WEP was small (ηp2 = 0.048)
  • WEP represents the anaerobic/glycolytic energy contribution above the critical power threshold

Peak power output was not significantly affected by any supplementation condition.

  • Peak power was not significantly different across conditions (p = 0.642, ηp2 = 0.046)
  • Effect size for peak power was small (ηp2 = 0.046)
  • This was a secondary outcome measure in the study

Mean power output and total work were not significantly affected by any supplementation condition.

  • Mean power output was not significantly different across conditions (p = 0.212, ηp2 = 0.108)
  • Total work was not significantly different across conditions (p = 0.217, ηp2 = 0.107)
  • Mean power and total work had the largest effect sizes of all measured outcomes (ηp2 = 0.108 and 0.107, respectively), though still non-significant
  • These were secondary outcome measures in the study

The study recruited trained male cyclists with moderate aerobic capacity as participants.

  • Fifteen healthy, trained male cyclists participated (n = 15)
  • Mean age was 28.5 ± 5.3 years and mean body mass was 79.2 ± 9.1 kg
  • VO2peak was 55.2 ± 5.6 mL·kg-1·min-1
  • Trials were separated by 3–7 days to allow for washout between conditions

What This Means

This research suggests that taking beetroot juice (a source of dietary nitrate) and/or caffeine before a high-intensity cycling test does not meaningfully improve key markers of cycling performance in trained male cyclists. Fifteen trained cyclists completed four separate exercise sessions under different supplement conditions — a placebo, beetroot juice alone, caffeine alone, and both combined — before performing a 3-minute maximal cycling effort. The main measures of interest were 'end power' (a proxy for critical power, or the highest sustainable exercise intensity) and the total extra work done above that threshold, but none of these outcomes differed significantly between conditions. The study used a rigorous double-blind, placebo-controlled, crossover design, meaning neither the participants nor the researchers knew which supplement was being taken during each trial, and every participant experienced all four conditions. Beetroot juice provided roughly 13 mmol of nitrate, and caffeine was dosed at 5 mg per kilogram of body weight — doses consistent with those used in previous research showing benefits in other populations or exercise protocols. Despite this, no statistically significant effects were found for any measured outcome, including peak power, mean power, or total work. This research suggests that the ergogenic (performance-enhancing) effects of dietary nitrate and caffeine, either alone or combined, may not extend to this specific type of short, maximal cycling effort in already-trained individuals. The relatively small sample size (15 participants) means the study may not have had enough statistical power to detect small but real effects, and the trained status of participants may have contributed to a ceiling effect where performance improvements are harder to achieve. These findings add nuance to the broader literature and highlight that supplement responses can vary depending on exercise modality, duration, and athlete training status.

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Citation

Hagele A, Sunderland K, Mumford P, Kerksick C. (2026). Effects of Dietary Nitrate and Caffeine on End Power and Work Above End Power During a 3 min All-Out Test in Trained Male Cyclists.. Nutrients. https://doi.org/10.3390/nu18091463