Effects of Psycho-Cardiology Model-Based Psychological and Behavioural Management on Negative Emotions and Sleep Disorders in Patients With Resistant Hypertension Complicated by Anxiety and Depression.
Zhu L & Hu W • Actas espanolas de psiquiatria • 2026
In this retrospective cohort of 126 patients with resistant hypertension complicated by anxiety and depression, the psycho-cardiology model combined with psychological and behavioural management was associated with milder negative emotions, better sleep status, improved autonomic function and more stable blood pressure profiles.
Key Findings
Results
At the end of follow-up, patients managed under the psycho-cardiology model had significantly lower anxiety scores than patients receiving regular management.
Anxiety was measured with the Hamilton Anxiety Rating Scale (HAMA).
The abstract reports the psycho-cardiology group's scores were 'significantly lower' than the regular group (p < 0.05).
The cohort comprised 126 patients, 63 per group, treated at Tonglu Hospital between August 2022 and May 2025.
Results
At the end of follow-up, the psycho-cardiology group had significantly lower depression scores than the regular group.
Depression was measured with the Hamilton Depression Rating Scale (HAMD).
The difference between groups was reported as p < 0.05.
Both groups received routine cardiovascular treatment; the psycho-cardiology group also received systematically documented psychological and behavioural management.
Results
Sleep quality was better in the psycho-cardiology group at the end of follow-up, as indicated by lower Pittsburgh Sleep Quality Index scores.
Lower PSQI scores indicate better sleep quality.
The abstract reports the between-group difference as p < 0.05.
Sleep disorder was one of the main outcomes alongside anxiety and depression.
Results
Blood pressure reductions, both systolic and diastolic, were greater in the psycho-cardiology group than in the regular group.
Reported significance was p < 0.05 for both systolic and diastolic blood pressure reductions.
Authors describe more stable blood pressure profiles in the psycho-cardiology group.
Patients had resistant hypertension, so the comparison was on top of routine cardiovascular treatment.
Methods
The study was a retrospective cohort in which group assignment was determined by documentation in medical records rather than randomization.
Patients were divided according to whether psycho-cardiology model-related assessment and psychological/behavioural management were systematically documented in their records.
126 patients met predefined inclusion criteria, split into psycho-cardiology (n = 63) and regular (n = 63) groups.
Data came from electronic medical records and follow-up data from the Department of Cardiology, Tonglu Hospital, Hangzhou First People's Hospital Tonglu Campus.
Conclusions
The authors conclude that the psycho-cardiology model was associated with improved autonomic function in addition to milder negative emotions and better sleep.
The conclusion states associations 'in this retrospective cohort', not causation.
Autonomic function improvement is mentioned in the conclusion; no specific measures or values appear in the abstract.
What This Means
This study looked back at the records of 126 patients with resistant hypertension (high blood pressure that is hard to control) who also had anxiety and depression. Half had received a 'psycho-cardiology' approach, which combines heart care with systematic psychological and behavioural management, on top of usual cardiovascular treatment. The other half received regular care.
By the end of follow-up, the psycho-cardiology group had lower anxiety, depression and sleep-problem scores, and larger drops in both systolic and diastolic blood pressure, than the regular-care group. The authors also describe improved autonomic function and more stable blood pressure.
This research suggests that attending to mental health and behaviour alongside blood pressure treatment may be linked to better outcomes in this group. However, the study was retrospective, and patients were grouped by how their care was documented rather than randomly assigned, so it shows an association and cannot prove the approach caused the improvements. Prospective, randomized studies would be needed to confirm the findings.
Zhu L, Hu W. (2026). Effects of Psycho-Cardiology Model-Based Psychological and Behavioural Management on Negative Emotions and Sleep Disorders in Patients With Resistant Hypertension Complicated by Anxiety and Depression.. Actas espanolas de psiquiatria. https://doi.org/10.62641/aep.2241