Goal-directed rehabilitation achieved larger gains in activities of daily living and motor function compared with conventional rehabilitation in cerebral infarction patients, suggesting that integrating individualized, explicitly defined rehabilitation goals into multidisciplinary stroke rehabilitation may enhance short-term functional recovery.
Key Findings
Results
Both rehabilitation groups showed significant improvements across functional domains, but the goal-directed rehabilitation group achieved larger gains in activities of daily living as measured by the Barthel index.
Barthel index improvement: +25.0 in the goal-directed group vs +18.0 in the conventional group (P < .001)
185 patients admitted for rehabilitation between January 2023 and December 2024 were included in the retrospective cohort study
Outcomes were assessed at admission and discharge using standardized instruments
The goal-directed rehabilitation framework was implemented in 2024, with the 2023 cohort serving as the conventional rehabilitation comparator
Results
The goal-directed rehabilitation group achieved larger gains in motor function as measured by the Fugl-Meyer assessment compared to the conventional rehabilitation group.
Fugl-Meyer assessment improvement: +16.0 in the goal-directed group vs +11.0 in the conventional group (P < .001)
Staffing structure, therapist training background, rehabilitation intensity, and equipment conditions remained stable across the study period
Both groups showed significant improvements in motor function
Results
Improvements in balance, gait performance, communication, and swallowing were more pronounced in the goal-directed rehabilitation group.
Outcomes assessed included Berg balance scale, walking distance, walking speed, communication ability, and bedside swallowing evaluation
Both groups showed significant improvements across all functional domains assessed
The goal-directed group demonstrated more pronounced improvements across these additional functional domains beyond ADLs and motor function
Discussion
The study was a single-center retrospective cohort design with findings limited to short-term inpatient rehabilitation outcomes.
The study enrolled 185 patients from a single center
The retrospective design and single-center setting limit generalizability
Findings reflect short-term inpatient rehabilitation outcomes only, with no long-term follow-up reported
Authors note that 'prospective multicenter studies with longer follow-up are required to confirm these observations'
Conclusions
Integrating individualized, explicitly defined rehabilitation goals into multidisciplinary stroke rehabilitation may enhance short-term functional recovery in cerebral infarction patients.
Apart from the goal-directed framework implementation, all other conditions including staffing, training, intensity, and equipment remained stable, providing some basis for attributing differences to the intervention
The goal-directed rehabilitation program was described as a 'structured goal-directed rehabilitation framework'
Rehabilitation was conducted in an inpatient recovery setting
The study period spanned January 2023 to December 2024
Zhang W, Li M, Yang B, Zhang W. (2026). Efficacy of goal-directed rehabilitation on functional recovery in patients with cerebral infarction.. Medicine. https://doi.org/10.1097/MD.0000000000047914