Aging & Longevity

[Expert consensus on testosterone supplementation to alleviate aging-related symptoms in men (2026 edition)].

TL;DR

A Chinese multidisciplinary expert panel formulated 21 recommendations to guide clinicians on the scientific and standardized use of testosterone supplementation to alleviate aging-related symptoms in men.

Key Findings

The consensus was developed by the Male Health Management Branch of the Chinese Health Management Association using a multidisciplinary expert group.

  • Experts came from endocrinology, andrology, traditional Chinese medicine, nutrition and other disciplines.
  • The recommendations are based on the latest evidence-based medical evidence, according to the abstract.

The consensus produced 21 recommendations covering the key issues of testosterone supplementation for aging-related symptoms in men.

  • Topics: ameliorating aging-related symptoms, appropriate candidates, risk assessment, medication strategies, and monitoring protocols.
  • The abstract does not report the content, strength, or evidence grade of the individual recommendations.

The consensus states that testosterone levels gradually decline in men with advancing age.

  • Aging is described as frequently accompanied by symptoms and physiological changes that impair men's quality of life.
  • Alleviating these symptoms is framed as an important public-health goal.

The consensus states that accumulating recent evidence suggests exogenous testosterone supplementation may ameliorate selected aging-related symptoms and enhance men's health status.

  • The wording is limited to 'selected' symptoms and 'may' ameliorate, indicating partial and not universal benefit.
  • The abstract does not name the specific symptoms or give effect sizes.

The stated aim is to give clinicians guidance on the scientific and standardized application of testosterone supplementation to alleviate aging-related symptoms in men.

  • The document is intended for clinical practice and covers patient selection, risk assessment, treatment strategy and monitoring.

What This Means

This is an expert consensus statement, not a clinical trial. A group of Chinese specialists in hormone medicine, men's health, traditional Chinese medicine, and nutrition reviewed current evidence and wrote 21 recommendations on using testosterone supplements to ease symptoms linked to aging in men. The statement notes that men's testosterone levels gradually fall with age, and that recent evidence suggests supplementing testosterone may relieve some aging-related symptoms and improve health status. The recommendations cover who may be suitable for treatment, how to assess risks, how treatment might be given, and how to monitor patients over time. This research suggests that testosterone supplementation is being approached as something that needs careful patient selection, risk assessment, and follow-up. The abstract does not give the details of the 21 recommendations, which symptoms may improve, or how strong the evidence is, so the full document would be needed for those specifics. It is a guide for clinicians and not a substitute for individual medical advice.

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Citation

(2026). [Expert consensus on testosterone supplementation to alleviate aging-related symptoms in men (2026 edition)].. Zhonghua yi xue za zhi. https://doi.org/10.3760/cma.j.cn112137-20260624-01670