Cardiovascular

Exploring the multifactorial reasons for treatment-seeking delays among young and middle-aged stroke patients: a qualitative study.

TL;DR

Treatment-seeking delay among young and middle-aged stroke patients arises through dynamic interactions across socioecological strata rather than isolated factors, characterized as a sequential cascade mediated by cognitive misattribution, emotional paralysis, relational dependency, institutional constraints and cross-level feedback loops.

Key Findings

Data analysis revealed five overarching themes encompassing 12 subthemes that explain treatment-seeking delays among young and middle-aged stroke patients.

  • The five themes were: (1) limited stroke-specific health literacy; (2) psychological barriers at symptom onset; (3) inadequate interpersonal support systems; (4) structural impediments to timely care; (5) decision-making dynamics across levels.
  • Analysis was conducted using a descriptive phenomenological approach.
  • The socioecological model was used as the organizing framework to identify barriers at individual, interpersonal, and systemic levels.
  • Themes were derived from dyadic semistructured interviews with both patients and family members.

Treatment-seeking delay was characterized as a sequential cascade mediated by multiple interacting factors across socioecological levels.

  • The cascade was mediated by cognitive misattribution, emotional paralysis, relational dependency, institutional constraints, and cross-level feedback loops.
  • Two dominant pathways were identified: 'silent progression' and 'diverted seeking.'
  • Delays were shaped by interlevel interactions rather than isolated factors.
  • The framework revealed how cross-level feedback loops shaped decision-making trajectories.

The study recruited 20 acute stroke patients with treatment-seeking delays and 16 family members from a tertiary hospital in China.

  • Participants were young and middle-aged stroke patients.
  • Dyadic semistructured interviews were conducted with both patients and their family members.
  • The study was conducted at a single tertiary hospital in China.
  • A descriptive phenomenological interview study design was used.

Integrated interventions targeting multiple socioecological levels are required to disrupt the delay cascade.

  • Recommended intervention targets include public awareness, familial preparedness, workplace policies, and healthcare accessibility.
  • The authors concluded that no single-level intervention would be sufficient given the multifactorial and interactive nature of delays.
  • The findings suggest that both individual and systemic factors must be addressed simultaneously.
  • Cross-level interactions were identified as shaping decision-making trajectories, indicating that interventions must account for these dynamics.

Limited stroke-specific health literacy at the individual level was identified as a contributor to treatment-seeking delays.

  • This was identified as one of the five overarching themes derived from qualitative analysis.
  • Cognitive misattribution was described as one mechanism within the delay cascade, suggesting patients misidentified or minimized stroke symptoms.
  • Limited health literacy operated at the individual level within the socioecological framework.
  • This factor interacted with other levels through cross-level feedback loops to shape overall delay behavior.

Psychological barriers at symptom onset, including emotional paralysis, contributed to treatment-seeking delays.

  • Emotional paralysis was identified as one of the mediating factors in the sequential delay cascade.
  • Psychological barriers were categorized as operating at the individual level of the socioecological model.
  • This theme was one of five overarching themes identified across the 12 subthemes.
  • Psychological responses at symptom onset interacted with interpersonal and systemic factors to shape delay trajectories.

Inadequate interpersonal support systems and relational dependency were identified as interpersonal-level barriers to timely treatment-seeking.

  • Relational dependency was named as one of the mediating mechanisms in the delay cascade.
  • Inadequate interpersonal support systems constituted one of the five overarching themes.
  • Family members were included as study participants through dyadic interviews, reflecting the role of interpersonal dynamics in delays.
  • Interpersonal factors interacted with individual and systemic levels through cross-level feedback loops.

Structural impediments at the systemic level, including institutional constraints, contributed to treatment-seeking delays.

  • Structural impediments to timely care was identified as one of the five overarching themes.
  • Institutional constraints were named as one of the mediating mechanisms in the delay cascade.
  • Systemic factors included healthcare accessibility issues.
  • Workplace policies were also identified as a systemic factor requiring intervention to reduce delays.

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Citation

Yang Q, Fang C, Wang X, Huang S, Li L, Tian C. (2026). Exploring the multifactorial reasons for treatment-seeking delays among young and middle-aged stroke patients: a qualitative study.. BMJ open. https://doi.org/10.1136/bmjopen-2025-111267