Sexual Health

Exploring the use of artificial intelligence in the promotion of sexual health: a cross-sectional assessment.

TL;DR

Many individuals are willing to consider AI technology use for sexual health promotion, however issues related to trust and security should be addressed to optimize uptake.

Key Findings

A majority of participants at a safety-net sexual health clinic had previously used AI tools for health or other information.

  • 67% of participants reported having previously used AI such as ChatGPT, Google Bard, and/or Fandango for topics related to health information, school, or customer service.
  • 15% reported using AI technology an average of once a month, 14% once a week, and 11% daily.
  • Sample size was 100 individuals presenting to a safety-net sexual health clinic in 2025.
  • The survey was a short, one-time anonymous cross-sectional survey.

Demographic variables were not significantly associated with preference for AI-based versus clinic-based sexual health counseling.

  • Multiple linear regression analyses were conducted to examine the association between demographic factors and counseling preference.
  • The association between demographic variables and preference for AI versus clinic-based counseling was not statistically significant (p = 0.21).
  • The study population included 17% African American/Black and 11% Hispanic/Latino participants.
  • 84% of participants self-identified as LGBTQ+.

A majority of participants reported distrust regarding sharing personal information with AI technology.

  • 56% of respondents reported distrust regarding sharing personal information with AI technology.
  • This was identified as a key barrier to AI uptake for sexual health promotion.
  • The study focused on underserved populations who are disproportionately impacted by sexual health disparities.
  • The setting was a safety-net sexual health clinic, reflecting a population with limited access to traditional healthcare resources.

The study population was predominantly LGBTQ+ and reflected racial and ethnic minority groups disproportionately impacted by sexual health disparities.

  • 84% of participants self-identified as LGBTQ+.
  • 17% of participants were African American/Black and 11% were Hispanic/Latino.
  • The clinic was described as a safety-net sexual health clinic serving underserved populations.
  • Total sample size was 100 individuals surveyed in 2025.

Many individuals expressed willingness to consider AI technology for sexual health promotion despite noted concerns about trust and privacy.

  • The authors concluded that 'many individuals are willing to consider AI technology use for sexual health promotion.'
  • Trust and security were identified as the primary barriers that 'should be addressed to optimize uptake.'
  • The study explored both facilitators and barriers of AI use with a focus on underserved populations.
  • AI was described as 'an emerging approach in addressing sexual health including HIV and other sexually transmitted infections (STIs).'

What This Means

This research surveyed 100 people at a safety-net sexual health clinic to understand how they feel about using artificial intelligence (AI) tools — like ChatGPT — to get information and support related to sexual health, HIV, and sexually transmitted infections. The majority of participants already had experience using AI for various purposes, and many said they would be open to using it for sexual health promotion. Notably, preference for AI versus in-person clinic counseling did not differ significantly based on demographic factors such as race, ethnicity, or sexual identity, suggesting broad openness to AI across groups. However, more than half of participants (56%) expressed distrust about sharing personal information with AI systems, which was identified as a major barrier to wider adoption. The study population was largely LGBTQ+ (84%) and included racial and ethnic minority groups who are often disproportionately affected by sexual health disparities and may face barriers to accessing traditional healthcare. This research suggests that AI tools could be a viable supplement to traditional sexual health services, particularly for underserved populations who may have limited access to clinics or who prefer anonymous information-seeking. At the same time, for AI to be effectively adopted in this context, developers and healthcare providers would need to meaningfully address concerns about data privacy, confidentiality, and trust.

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Citation

Maguire-Wilkerson A, Parent H, Tao J, Chan P. (2026). Exploring the use of artificial intelligence in the promotion of sexual health: a cross-sectional assessment.. International journal of STD & AIDS. https://doi.org/10.1177/09564624251411095