Factors affecting cost-related medication non-adherence among US population with cardiovascular risk factors.

Insurance coverage was strongly associated with lower cost-related medication non-adherence compared to being uninsured.

• Public insurance participants had lower CRMN than uninsured (OR 0.13, 95% CI, 0.04-0.45)
• Medicaid participants also had lower CRMN than uninsured (OR 0.24, 95% CI, 0.15-0.36)
• Study population included 49,464 participants from the 2019-2021 National Health Interview Survey (NHIS)
• Logistic regression was used to determine factors associated with CRMN

High income was associated with lower odds of CRMN across all three CVD risk factor subgroups examined.

• Among participants with diabetes, high-income had lower odds of CRMN (OR 0.38, 95% CI, 0.28-0.50) compared to lower-income
• Among participants with hypertension, high-income had lower odds of CRMN (OR 0.39, 95% CI, 0.28-0.58) compared to lower-income
• Among participants with hyperlipidemia, high-income had lower odds of CRMN (OR 0.37, 95% CI, 0.27-0.51) compared to lower-income
• Stratified analysis was conducted by diabetes, hypertension, and hyperlipidemia

Younger adults (under 65) had higher CRMN, while those aged 65 or older had lower CRMN.

• Adults aged 65 or older had lower CRMN than younger participants
• Adults under 65 with more CVD risk factors and lacking insurance coverage were identified as being at higher risk of CRMN
• Age was analyzed using chi-square tests and logistic regression

Demographic and socioeconomic characteristics including sex, marital status, education, and geographic region were associated with CRMN.

• Young, unmarried individuals, females, and less educated participants had higher CRMN than older, married individuals, males, and those with higher education
• Participants from the South had higher CRMN than those residing in other regions
• Those with excellent self-rated health had lower CRMN than those with poor self-rated health
• Data were drawn from CDC's 2019-2021 National Health Interview Survey

Smoking status and number of CVD risk factors were associated with higher CRMN.

• Current smokers reported higher CRMN than former and never-smokers
• Participants with more CVD risk factors reported higher CRMN than those with fewer risk factors
• Participants were categorized into three groups based on reported CVD risk factors
• Chi-square tests were used to assess these associations