Cardiovascular

Food Insecurity and Cardiovascular-Kidney-Metabolic Syndrome-Related Conditions Among US Adults, National Health and Nutrition Examination Survey, 2015-2020.

TL;DR

Food insecurity is significantly associated with CKM syndrome-related conditions among US adults, with very low food security associated with substantially higher odds of congestive heart failure, coronary heart disease, heart attack, and stroke, and dose-response relationships observed across multiple cardiometabolic outcomes.

Key Findings

Approximately 28.4% of US adult respondents experienced some level of food insecurity (marginal, low, or very low food security).

  • Total sample size was 13,937 US adult participants from the 2015-2020 National Health and Nutrition Examination Survey (NHANES).
  • Mean age of respondents was 47.4 years and mean BMI was 29.6.
  • Food insecurity status was self-reported via questionnaire.
  • The study used a cross-sectional design.

Obesity, hyperglycemia, and hypertension were the most prevalent cardiometabolic conditions in the sample.

  • Obesity prevalence was 40.9% among total respondents.
  • Hyperglycemia prevalence was 58.9% among total respondents.
  • Hypertension prevalence was 29.9% among total respondents.
  • These conditions are components of cardiovascular-kidney-metabolic (CKM) syndrome.

Very low food security was associated with substantially higher odds of multiple cardiovascular diseases compared with full food security.

  • Very low food security was associated with higher odds of congestive heart failure (AOR = 3.69).
  • Very low food security was associated with higher odds of coronary heart disease (AOR = 3.43).
  • Very low food security was associated with higher odds of heart attack (AOR = 3.21).
  • Very low food security was associated with higher odds of stroke (AOR = 2.54).
  • Models were adjusted for demographic variables and socioeconomic status.

Lower food security was associated with significantly higher odds of obesity, diabetes, weak or failing kidneys, and cardiovascular diseases, with clear dose-response relationships.

  • Dose-response relationships were observed across multiple CKM syndrome-related conditions as food security level decreased.
  • Weighted logistic regression models were used to examine these associations.
  • Adjustments were made for demographic variables and socioeconomic status.
  • The dose-response pattern held across the spectrum from marginal to very low food security.

The likelihood of low or very low food security increased stepwise with the number of coexisting cardiovascular diseases.

  • Adults reporting 4 coexisting CVDs had the highest odds of low or very low food security (AOR = 3.93).
  • The relationship between number of coexisting CVDs and food insecurity was stepwise, indicating a dose-response pattern.
  • This finding suggests a bidirectional or cumulative relationship between food insecurity and cardiovascular disease burden.

What This Means

This research suggests that food insecurity — not having reliable access to enough food — is strongly linked to a cluster of serious health conditions in US adults, including heart disease, diabetes, obesity, and kidney problems. Using data from nearly 14,000 adults surveyed between 2015 and 2020, researchers found that people with the lowest food security were more than three times as likely to have congestive heart failure or coronary heart disease, and more than twice as likely to have had a stroke, compared to people with full food security. Importantly, the associations followed a dose-response pattern, meaning the worse a person's food security, the higher their risk of these conditions. The study also found that having more cardiovascular conditions at the same time was associated with greater food insecurity — people with four coexisting heart-related conditions were nearly four times as likely to experience low or very low food security. Common conditions in the sample included high rates of obesity (about 41%), elevated blood sugar (nearly 59%), and high blood pressure (about 30%), underscoring how widespread these health challenges are among US adults. This research suggests that food insecurity is not just a social or economic issue but a significant factor tied to serious chronic diseases. Addressing food access and affordability could be an important component of efforts to reduce the burden of heart, kidney, and metabolic diseases in the United States, particularly among vulnerable populations.

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Citation

Ernest D, Singh B, Hinojosa A, Imran A, Onugha E, Sharma S, et al.. (2026). Food Insecurity and Cardiovascular-Kidney-Metabolic Syndrome-Related Conditions Among US Adults, National Health and Nutrition Examination Survey, 2015-2020.. Preventing chronic disease. https://doi.org/10.5888/pcd23.250372