Compared with pain-free controls, individuals with chronic metatarsalgia showed greater plantar pressure under the lateral midfoot, 1st metatarsal head and toes, greater ankle eversion, knee and hip flexion, and greater ankle plantarflexion moments during level walking, suggesting compensatory mechanisms in response to forefoot pain.
Key Findings
Results
Individuals with chronic metatarsalgia showed significantly greater maximum within-mask pressure under the lateral midfoot, 1st metatarsal head and the toes during stance than controls.
Maximum within-mask pressure was measured in nine foot regions during level walking.
Group comparisons used two-sample t-tests with statistical parametric mapping.
The abstract reports these differences as significant during the stance phase.
Results
Ankle eversion angles were significantly greater in individuals with chronic metatarsalgia than in controls.
This contrasts with the hypothesis of reduced ankle pronation in the CM group.
Three-dimensional kinematics of the midfoot, ankle, knee and hip were compared using statistical parametric mapping.
Results
Knee and hip flexion angles were significantly greater in the chronic metatarsalgia group than in controls during walking.
Kinematics were computed during level walking and compared with two-sample t-tests using statistical parametric mapping.
The authors interpret the proximal differences as potential compensatory mechanisms in response to forefoot pain.
Results
Ankle plantarflexion moments were significantly greater in individuals with chronic metatarsalgia than in controls.
Internal joint moments were calculated in the sagittal, frontal and transverse planes.
The hypothesis of increased midfoot dorsiflexion moments is not reported as supported in the abstract; the abstract only reports greater ankle plantarflexion moments.
Methods
The study was a case-control comparison of 23 individuals with chronic metatarsalgia and 23 pain-free controls with matched sex distribution.
Each group included 17 females and 6 males.
Controls had no lower limb pain.
Outcomes included plantar pressure in nine foot regions, 3D kinematics (midfoot, ankle, knee, hip) and kinetics.
Conclusions
The authors conclude that the biomechanical differences suggest compensatory mechanisms in response to forefoot pain and that individualized biomechanical and clinical assessment is needed to guide orthotic and therapeutic strategies.
Most existing treatments focus on reducing forefoot plantar pressure.
Prior to this study, no study had identified a link between chronic metatarsalgia and metatarsal head overload during level walking.
What This Means
This study compared how 23 people with long-lasting forefoot pain (chronic metatarsalgia) and 23 people without leg pain walk. Researchers measured the pressure under different parts of the foot and the movement and forces at the foot, ankle, knee and hip.
People with chronic metatarsalgia had higher pressure under the outer middle part of the foot, the base of the big toe (1st metatarsal head) and the toes. They also showed more ankle eversion (the ankle rolling inward), more bending at the knee and hip, and larger forces pushing the ankle toward pointing the foot downward (plantarflexion moments).
The authors suggest these differences may be ways the body adapts to forefoot pain. This research suggests that treatments aimed only at reducing forefoot pressure may not address the whole picture, and that individualized assessment of how a person walks may help guide orthotic and therapy choices. The study compared groups at one point in time, so it cannot show whether these walking patterns cause the pain or result from it.
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Payen Schalkens E, Acien M, Isabelle P, Turcot K, Begon M, Abboud J, et al.. (2026). Gait biomechanics in individuals with chronic metatarsalgia: A case-control study.. Journal of biomechanics. https://doi.org/10.1016/j.jbiomech.2026.113620