Hospice care can effectively alleviate pain, sleep disorders, anxiety and depression in elderly cancer chemotherapy survivors, improve their quality of life, reduce adverse reactions and readmission rate and enhance nursing satisfaction and is thus worthy of clinical promotion.
Key Findings
Results
Post-intervention pain scores were significantly lower in the hospice care group compared to the routine nursing group.
Visual Analogue Scale (VAS) scores post-intervention: observation group 2.08 ± 0.85 vs. control group 4.68 ± 1.33 (p < 0.05)
Pre-intervention, no significant differences were found between groups (p > 0.05)
Study enrolled 240 elderly cancer survivors who completed at least 4 cycles of chemotherapy, with 98 cases per group after 1:1 propensity score matching
Results
Sleep quality was significantly better in the hospice care group than the routine nursing group after intervention.
Pittsburgh Sleep Quality Index (PSQI) scores post-intervention: observation group 5.25 ± 1.32 vs. control group 8.92 ± 1.65 (p < 0.05)
Lower PSQI scores indicate better sleep quality
Groups were comparable at baseline with no significant pre-intervention differences
Results
Anxiety levels were significantly reduced in the hospice care group compared to the control group after intervention.
Self-rating Anxiety Scale (SAS) scores post-intervention: observation group 38.15 ± 4.15 vs. control group 49.32 ± 5.40 (p < 0.05)
The difference represents a clinically meaningful reduction in anxiety symptoms
Participants were elderly cancer survivors followed up over a 3-month period from January 2022 to June 2024
Results
Depression scores were significantly lower in the hospice care group than the routine nursing group after intervention.
Self-rating Depression Scale (SDS) scores post-intervention: observation group 38.86 ± 4.40 vs. control group 50.65 ± 5.80 (p < 0.05)
Pre-intervention SDS scores did not differ significantly between groups (p > 0.05)
Both anxiety and depression outcomes were measured using validated self-rating scales
Results
The hospice care group showed significant improvements in all eight dimensions of the SF-36 quality of life measure, with a larger improvement range than the control group.
All eight SF-36 dimensions showed significant improvement in the observation group (p < 0.05)
The observation group had a larger improvement range than the control group across all SF-36 dimensions
The SF-36 (Short Form-36 Health Survey) was used as the primary quality of life measurement tool
Results
The hospice care group had lower incidence of chemotherapy-related adverse reactions than the control group.
Nausea and vomiting incidence: observation group 8.16% vs. control group 24.49% (p < 0.05)
Fatigue incidence: observation group 16.33% vs. control group 31.63% (p < 0.05)
These differences were statistically significant (all p < 0.05)
Results
The hospice care group had a significantly lower 3-month readmission rate compared to the control group.
3-month readmission rate: observation group 7.14% vs. control group 19.39% (p < 0.05)
Follow-up period was 3 months post-intervention
Readmission rate was one of the extended indicators assessed in the study
Results
Nursing satisfaction was significantly higher in the hospice care group than in the routine nursing group.
Nursing satisfaction rate: observation group 95.92% vs. control group 82.65% (p < 0.05)
Nursing satisfaction was measured as one of the extended indicators alongside adverse reactions and readmission rate
This difference was statistically significant (p < 0.05)
Methods
The study used propensity score matching to control for baseline differences between the hospice care and routine nursing groups.
Original enrollment included 124 patients in the observation group and 116 in the control group
After 1:1 propensity score matching, 98 cases per group were analysed
Pre-intervention scores on all core indicators (VAS, PSQI, SAS, SDS, SF-36) showed no significant differences between groups (p > 0.05)
Study was retrospective, enrolling patients from January 2022 to June 2024 who completed at least 4 cycles of chemotherapy
What This Means
This research suggests that adding hospice care to standard nursing routines significantly benefits elderly cancer survivors who have completed chemotherapy. The study compared 98 patients who received hospice care alongside routine nursing to 98 patients who received only routine nursing. After the intervention, those who received hospice care reported much lower levels of pain, better sleep quality, and substantially reduced anxiety and depression scores compared to the control group. They also showed greater improvements across all eight areas of a standard quality-of-life survey.
Beyond psychological and pain outcomes, the hospice care group also experienced fewer physical complications from chemotherapy, including lower rates of nausea, vomiting, and fatigue. Importantly, far fewer patients in the hospice care group needed to be readmitted to the hospital within 3 months (about 7% compared to nearly 20% in the control group). Patients receiving hospice care also reported higher satisfaction with their nursing care overall (about 96% versus 83%).
This research suggests that integrating hospice care principles—which typically focus on comfort, emotional support, and holistic well-being—into post-chemotherapy care for elderly patients could lead to meaningful improvements across multiple aspects of health and well-being. The findings indicate potential benefits not only for patients' physical and mental health but also for healthcare systems through reduced hospital readmissions. The authors conclude this nursing model is worthy of broader clinical adoption, though the retrospective design of the study means further prospective research would strengthen these conclusions.
Cao W, Wang H. (2026). Hospice Care's Influence on Pain, Sleep, Anxiety, and Depression: A Focus on Elderly Survivors of Cancer Chemotherapy.. Actas espanolas de psiquiatria. https://doi.org/10.62641/aep.v54i1.2082