Gastric and jejunal loop dilation caused ST-segment elevation in inferolateral leads mimicking STEMI, which resolved after gastric decompression, suggesting cardiac external compression as the mechanism.
Key Findings
Background
A man in his 70s presented with ST-segment elevation in inferolateral leads on ECG associated with nausea, vomiting, and epigastric discomfort.
The patient presented with nausea, vomiting, and epigastric discomfort
ECG showed ST-segment elevation in the inferolateral leads
The presentation mimicked ST-elevation myocardial infarction (STEMI)
Results
Coronary angiography revealed no coronary artery stenoses, ruling out obstructive coronary artery disease as the cause of ST-segment elevation.
No coronary artery stenoses were found on coronary evaluation
This finding excluded a primary ischemic etiology for the ECG changes
Results
CT scan identified gastric and jejunal loop dilation as the underlying cause of the ST-segment elevation.
CT scan displayed gastric and jejunal loop dilation
The imaging finding indicated ileus as the precipitating condition
Mild myocardial damage was also noted in association with the gastric dilation
Results
ST-segment elevation resolved after gastric decompression, confirming the causal relationship between gastric dilation and ECG changes.
The ECG returned to normal after gastric decompression
Resolution of ECG abnormalities following decompression supports a mechanistic link between gastric dilation and the cardiac findings
Discussion
The authors propose that cardiac external compression and myocardial injury from gastric dilation is the likely mechanism for the ST-segment elevation.
Authors state findings are 'likely related to cardiac external compression and injury on a limited myocardial region'
Several mechanisms might be implicated, though external compression was considered most likely
The case demonstrates that gastric compression on the heart is a non-cardiac cause of ST-segment elevation and mild myocardial damage
Conclusions
The authors recommend investigating gastric dilation as a non-cardiac cause of ST-segment elevation after ruling out myocardial infarction in suggestive clinical presentations.
Physicians must investigate gastric dilation after ruling out myocardial infarction in case of a suggestive clinical presentation
The case underscores gastric compression as a recognized non-cardiac etiology of ST-segment elevation
Clinical presentation features such as nausea, vomiting, and epigastric discomfort should prompt consideration of this diagnosis
Lemoli M, Mesi A, Petroboni B, Agabiti Rosei C. (2026). Ileus causing STEMI electrocardiographic findings.. BMJ case reports. https://doi.org/10.1136/bcr-2025-269546