Exercise & Training

Impact of ADHD on Obesity Treatment Outcomes in Adolescents Receiving Multidisciplinary Care: A Retrospective Longitudinal Study.

TL;DR

Although adolescents with and without ADHD may exhibit similar treatment outcomes, predictors of weight loss success differed, highlighting the importance of tailoring obesity programs according to behavioural and clinical profiles in order to improve obesity treatment among adolescents.

Key Findings

ADHD was present in 19.7% of adolescents followed at a tertiary Adolescent Obesity Clinic.

  • Total sample included 269 adolescents aged 12-17 years
  • 53 of 269 adolescents had ADHD (19.7%)
  • Participants were followed for a median of 16.8 months (IQR: 5.3)
  • This was a retrospective longitudinal study at a tertiary care clinic

Overall weight loss success was achieved in 34.9% of the sample, with no significant differences between adolescents with and without ADHD.

  • Weight loss success was defined as a decrease in BMI z-score of ≥0.25
  • 34.9% of the total sample achieved this threshold
  • No statistically significant difference in weight loss success rates was found between the ADHD and non-ADHD groups
  • Longitudinal changes were analyzed using generalised estimating equations

Among adolescents with ADHD, psychopathology was negatively associated with weight loss success.

  • Psychopathology was associated with reduced likelihood of weight loss success in the ADHD group (OR = 0.25)
  • This finding was identified using logistic regression models
  • The association suggests that comorbid psychiatric symptoms may impede obesity treatment response in adolescents with ADHD

Among adolescents with ADHD, increases in total physical activity were positively associated with weight loss success.

  • Increased total physical activity was associated with greater likelihood of weight loss success in the ADHD group (OR = 1.01)
  • This was identified as a significant predictor using logistic regression models
  • Physical activity was the primary behavioral predictor of success in the ADHD subgroup

Among adolescents without ADHD, impulsive eating reduced the likelihood of weight loss success while improved eating behaviour increased it.

  • Impulsive eating was negatively associated with weight loss success in the non-ADHD group (OR = 0.33)
  • Improved eating behaviour was positively associated with weight loss success in the non-ADHD group (OR = 2.92)
  • Eating-related behaviors were the primary predictors of success in adolescents without ADHD, distinct from the physical activity and psychopathology predictors seen in the ADHD group

Predictors of weight loss success differed between adolescents with and without ADHD despite similar overall treatment outcomes.

  • The ADHD group showed psychopathology and physical activity as key predictors, while the non-ADHD group showed eating behavior variables as key predictors
  • This divergence in predictors was identified despite no significant difference in overall weight loss success rates between groups
  • Authors concluded this highlights the importance of tailoring obesity programs according to behavioural and clinical profiles

What This Means

This research suggests that among teenagers with obesity receiving specialized multidisciplinary care, having ADHD does not necessarily mean worse weight loss outcomes overall. In a study of 269 adolescents aged 12-17 followed for about 17 months at a specialized obesity clinic, roughly 35% achieved meaningful weight loss, and this proportion was similar whether or not the teen had ADHD (which was present in about 1 in 5 participants). However, what predicted success differed importantly between the two groups. For teenagers with ADHD, having additional mental health problems (psychopathology) made success less likely, while increasing physical activity made success more likely. For teenagers without ADHD, eating-related behaviors mattered most — impulsive eating reduced the chances of success, while improvements in eating behavior more than doubled the odds of achieving meaningful weight loss. This research suggests that obesity treatment programs for adolescents should not use a one-size-fits-all approach. Teens with ADHD may benefit most from interventions that address mental health conditions alongside increasing physical activity, while teens without ADHD may benefit most from targeted support around eating behaviors. Recognizing these different pathways to success could help clinicians personalize care and improve outcomes for teenagers struggling with obesity.

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Citation

Videira-Silva A, de Almeida I, Sendim V, Carmo F, Moeda S, Freira S, et al.. (2026). Impact of ADHD on Obesity Treatment Outcomes in Adolescents Receiving Multidisciplinary Care: A Retrospective Longitudinal Study.. Pediatric obesity. https://doi.org/10.1111/ijpo.70145