IMPACT OF GINGER SUPPLEMENTATION ON BLOOD PRESSURE AND GLUCOSE LEVELS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND CARDIOVASCULAR DISEASE.

Ginger supplementation significantly reduced hs-CRP levels in patients with T2DM and CVD.

• hs-CRP decreased by 20.5% from 4.69±0.27 to 3.73±0.14 mg/L (p < 0.01)
• The intervention group received ginger infusion administered two times a day for 4 months
• Measurements were taken at week 2 and week 9 using Roche Cobas analyzers
• The control group (n=40) did not receive ginger intervention

Ginger supplementation significantly reduced IL-6 levels in the intervention group.

• IL-6 decreased by 25.2% from 7.35±0.33 to 5.50±0.20 pg/mL (p < 0.01)
• This was the largest percentage reduction among the inflammatory markers measured
• The study involved 80 participants aged 27-44 years with mild dyslipidemia, hyperglycemia, and hypertension

PCT (procalcitonin) levels remained unchanged following ginger supplementation.

• PCT values were reported as 0.05±0.00 vs. 0.07±0.00 ng/mL
• PCT was one of three oral inflammatory markers measured alongside hs-CRP and IL-6
• The paper states 'PCT levels remained unchanged'

Ginger supplementation significantly improved lipid profiles, including reductions in total cholesterol, LDL-C, VLDL-C, and triglycerides.

• Total cholesterol decreased by 18.6% from 255.00±4.65 to 207.48±6.12 mg/dL (p < 0.01)
• LDL-C decreased by 6.7% from 172.63±2.31 to 161.05±2.50 mg/dL (p < 0.01)
• VLDL-C decreased by 17.9% from 44.69±1.19 to 36.71±1.10 mg/dL (p < 0.01)
• Triglycerides decreased by 13.6% from 222.25±4.49 to 191.90±4.49 mg/dL (p < 0.01)

Fasting glucose levels decreased significantly in the ginger supplementation group.

• The reduction in fasting glucose was statistically significant (p < 0.01)
• Specific baseline and follow-up fasting glucose values were not reported in the abstract
• Fasting glucose was measured using Roche Cobas analyzers at week 2 and week 9

The study design was a prospective interventional before-after study with a healthy reference control group.

• 80 total participants were enrolled, split into a control group (n=40) and an intervention group (n=40)
• Participants were aged 27-44 years and presented with mild dyslipidemia, hyperglycemia, and hypertension
• Ginger infusion was administered twice daily for 4 months
• Statistical analysis used paired t-tests with significance set at p < 0.05