Impact of Mango Puree Supplementation on Inflammatory, Muscle Damage, and Selected T-Cell Biomarkers in Elite Beach Volleyball Players During Regular Training.

Mango puree supplementation was associated with significantly lower C-reactive protein concentrations compared to placebo.

• Mean difference of -1.6 mg/L (95% CI: -2.1 to -1.1; p < 0.001)
• Outcomes analyzed using linear mixed-effects models
• Study design: pilot randomized, single-blind, crossover trial with 15 male athletes
• Supplementation dose was 600 g/day for 4 weeks

Mango puree supplementation was associated with significantly lower interleukin-6 concentrations compared to placebo.

• Mean difference of -0.7 pg/mL (95% CI: -1.2 to -0.3; p = 0.003)
• Participants were Thai men's national beach volleyball players
• Blood samples were collected at baseline and at the end of each intervention period
• A 2-week washout period separated the two intervention periods

Mango puree supplementation was associated with significantly lower creatine kinase concentrations compared to placebo.

• Mean difference of -290.1 U/L (95% CI: -356.1 to -224.1; p < 0.001)
• Creatine kinase was used as a marker of muscle damage
• The reduction in creatine kinase occurred during regular training conditions
• Fifteen male athletes completed the trial

The percentage of CD4+ T cells was significantly higher during mango puree supplementation compared to placebo.

• Mean difference of 9.82 percentage points (95% CI: 5.0 to 14.6; p < 0.001)
• CD8+ T-cell percentage did not differ significantly between conditions
• The CD4/CD8 ratio was also higher during mango supplementation (mean difference: 0.37; 95% CI: 0.11 to 0.63; p = 0.007)
• These findings indicate alterations in selected T-cell subsets associated with mango puree supplementation

No significant treatment effects were observed for body composition parameters or blood pressure.

• All p-values for body composition parameters and blood pressure were > 0.05
• Total energy intake remained unchanged across intervention periods (p > 0.05)
• The absence of body composition changes suggests the observed biomarker effects were not confounded by dietary energy changes
• Physiological measurements were collected alongside blood samples at baseline and end of each intervention period

The study was designed as a pilot randomized, single-blind, crossover trial in Thai men's national beach volleyball players.

• Fifteen male athletes completed the trial
• Participants consumed either mango puree or placebo at 600 g/day for 4 weeks
• A 2-week washout period separated the two intervention periods
• Mango is described as a tropical fruit rich in polyphenols and carotenoids that may support recovery-related physiological responses during athletic training