Intermittent Fasting May Enhance Resistance Training Effects on the Body Composition of Obese Males, Without Affecting Muscular Strength and Anabolic Index.
Farahmand Khoshkebijari A, Ebrahimi M, Jorbonian A • Journal of obesity • 2026
Intermittent fasting may enhance the efficacy of resistance training in obese males and is unlikely to have any detrimental effects on muscular strength or the anabolic index.
Key Findings
Results
The IF/RT group lost approximately twofold more weight than the control resistance training group.
Twenty obese males aged 20-30 with BMI 30-36 kg/m2 were randomly assigned to control (regular diet) or IF (4:3 IF) groups
All subjects participated in resistance training 3 days/week for 8 weeks
The IF/RT group lost twofold more weight than the C/RT group
Blood sampling and anthropometric measurements were conducted 48 hours before and after the protocol in a fasting state
Data were analyzed at a significance level of p < 0.05
Results
The IF/RT group lost approximately twofold more fat compared to the control resistance training group.
The 4:3 intermittent fasting protocol was combined with resistance training over 8 weeks
Fat loss was approximately twofold greater in the IF/RT group than in the C/RT group
The IF/RT group also had less waist circumference than the C/RT group
Anthropometric measurements were taken in a fasting state 48 hours before and after the protocol
Results
The IF/RT group had higher arm and chest measurements compared to the control resistance training group.
Arm and chest circumference measurements were greater in the IF/RT group than in the C/RT group
This finding suggests potential lean mass or muscle size improvements with the addition of intermittent fasting to resistance training
Measurements were taken 48 hours before and after the 8-week protocol
Results
Testosterone levels improved with resistance training but did not differ between the IF/RT and C/RT groups.
Testosterone levels improved following the resistance training protocol in both groups
There was no statistically significant difference between the C/RT and IF/RT groups for testosterone levels
Blood sampling was conducted 48 hours before and after the 8-week protocol in a fasting state
The testosterone:cortisol ratio (anabolic index) was assessed as an outcome measure
Results
Muscular strength improved with resistance training but did not differ between the IF/RT and C/RT groups.
Muscle strength improved following the resistance training protocol in both groups
There was no statistically significant difference in muscular strength between the C/RT and IF/RT groups
This finding indicates that intermittent fasting did not negatively impact strength gains from resistance training
The study used a randomized controlled trial design with significance level set at p < 0.05
Farahmand Khoshkebijari A, Ebrahimi M, Jorbonian A. (2026). Intermittent Fasting May Enhance Resistance Training Effects on the Body Composition of Obese Males, Without Affecting Muscular Strength and Anabolic Index.. Journal of obesity. https://doi.org/10.1155/jobe/6409069