Cardiovascular

Is adherence to the 24-hour movement guidelines related to a lower risk of cardiovascular events? A prospective cohort study including 13 897 participants from the SUN project.

TL;DR

Adherence to at least two of the three Canadian 24-hour movement guidelines (physical activity, sitting time, sleep) was associated with a lower risk of cardiovascular events than meeting none, in 13,897 Spanish university graduates from the SUN cohort.

Key Findings

Nearly half of SUN participants met all three 24-hour movement guidelines, and very few met none.

  • 46.68% of participants met all three guidelines.
  • Only 0.96% met none of the guidelines.
  • The analytic sample was 13,897 Spanish university graduates from the Seguimiento Universidad de Navarra (SUN) cohort.
  • Exposure was a composite score of 0-3 points based on the Canadian 24-Hour Movement Guidelines.

Meeting two of the three 24-hour movement guidelines was associated with a significantly lower risk of cardiovascular events than meeting none.

  • Fully adjusted hazard ratio was 0.37 (95% CI: 0.14-0.99) compared with meeting none.
  • 148 cardiovascular events occurred over a mean follow-up of 14.48 years.
  • The endpoint was incident CVD: nonfatal myocardial infarction, stroke, or cardiovascular death.

Meeting all three 24-hour movement guidelines was associated with a significantly lower risk of cardiovascular events than meeting none.

  • Fully adjusted hazard ratio was 0.36 (95% CI: 0.14-0.95) compared with meeting none.
  • The HR for three guidelines was similar to that for two (0.37), so the data show no clear additional benefit from the third guideline.
  • The confidence intervals are wide, reflecting the very small reference group (0.96% meeting none).

The study defined adherence using specific thresholds for physical activity, sitting time, and sleep duration.

  • Physical activity: ≥150 minutes/week of moderate-to-vigorous activity.
  • Sitting: ≤8 hours/day.
  • Sleep: 7-9 hours/night, or 7-8 hours for people aged ≥65 years.
  • Baseline questionnaires were completed from 1999, with biennial follow-up.

The authors conclude that adherence to at least two of the 24-hour movement guidelines appears associated with lower CVE risk, supporting an integrated approach to daily movement behaviors.

  • They suggest public health strategies could consider promoting the integrated guidelines as part of broader efforts to improve cardiovascular health.
  • The design is a prospective cohort, so the findings are associations rather than proof of causation.

What This Means

This study followed nearly 14,000 Spanish university graduates for an average of about 14.5 years to see whether following all three parts of the 24-hour movement guidelines related to heart disease. The guidelines cover getting at least 150 minutes a week of moderate-to-vigorous physical activity, sitting no more than 8 hours a day, and sleeping 7-9 hours a night (7-8 hours for people 65 and older). Nearly half of the participants met all three, and fewer than 1% met none. During follow-up, 148 heart attacks, strokes, or cardiovascular deaths occurred. Compared with people who met none of the guidelines, those who met two or all three had about a 63-64% lower risk of these events after accounting for other factors. The risk was similar whether people met two or three guidelines, so the data do not show a clear extra benefit from the third. This research suggests that combining healthy activity, limited sitting, and adequate sleep may be linked to better heart health. The results should be read cautiously: this was an observational study among highly educated adults, behaviors were self-reported, there were few events, and only a very small group met none of the guidelines, which makes the estimates imprecise. The study cannot prove that following the guidelines causes lower risk.

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Citation

Finnemore A, Soler R, Bes-Rastrollo M, Martínez-González M, Fernandez-Montero A. (2026). Is adherence to the 24-hour movement guidelines related to a lower risk of cardiovascular events? A prospective cohort study including 13 897 participants from the SUN project.. European journal of public health. https://doi.org/10.1093/eurpub/ckag191